Zhonghui Lin

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The DNA repair gene X-ray cross-complementary group 4 (XRCC4), an important caretaker of the overall genome stability, is thought to play a major role in human tumorigenesis. We investigated the association between an important polymorphic variant of this gene at codon 247 (rs373409) and diffusely infiltrating astrocytoma (DIA) risk and prognosis. This(More)
Hypertension is a common complication of type 2 diabetes mellitus (T2DM), and is the main cause for T2DM-associated mortality. Although the stringent control of blood pressure is known to be beneficial in reducing the cardiovascular mortality of T2DM patients, drugs with both anti-hypertensive and anti-hyperglycemic effects are seldom reported. The(More)
Keywords: VIP model Net ecosystem production Evapotranspiration Eddy covariance Uncertainty a b s t r a c t A process-based ecosystem model (Vegetationeatmosphere Interface Processes (VIP) model) is expanded, and then validated against three years' biometric, soil moisture and eddy-covariance fluxes data over a winter wheatesummer maize cropping system in(More)
To investigate the impacts of biophysical factors on light response of net ecosystem exchange (NEE), CO2 flux was measured using the eddy covariance technique in a winter wheat field in the North China Plain from 2003 to 2006. A rectangular hyperbolic function was used to describe NEE light response. Maximum photosynthetic capacity (P max) was 46.6 ± 4.0(More)
AIM des-O-methyllasiodiplodin (DML) from Cerbera manghas has shown antagonistic activity against mineralocorticoid receptor (MR). Considering the involvement of MR in the insulin tolerance, we attempted to investigate the potential of DML in the treatment of type 2 diabetes mellitus (T2DM). METHODS Surface plasmon resonance (SPR) technology and reporter(More)
Fibrinolysis is a process responsible for the dissolution of formed thrombi to re-establish blood flow after thrombus formation. Plasminogen activator inhibitor-1 (PAI-1) inhibits urokinase-type and tissue-type plasminogen activator (uPA and tPA) and is the major negative regulator of fibrinolysis. Inhibition of PAI-1 activity prevents thrombosis and(More)
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