Zhonghao Wang

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PURPOSE To compare the eye with chronic primary angle-closure glaucoma (CPACG) with its fellow eye without glaucoma damage and to determine the biometric differences that may predispose to development of CPACG. METHODS Consecutive patients diagnosed with CPACG in 1 eye and primary angle-closure (PAC)/primary angle-closure suspected (PACS) in the fellow(More)
PURPOSE To investigate the paired box 6 (PAX6) gene in two sporadic patients from southern China presenting with classic aniridia. METHODS The two sporadic patients underwent complete physical and ophthalmic examinations. Genomic DNA was extracted from the leukocytes of the peripheral blood collected from the families of the two sporadic patients and 100(More)
PURPOSE To compare the structural differences of the ciliary body in patients with acute primary-angle closure (APAC) and normal subjects. METHODS Forty-four patients with APAC in one eye and 25 eyes from 25 age-matched normal subjects were consecutively recruited. A-scan ultrasound and ultrasound biomicroscopy (UBM) measurements were performed. Ciliary(More)
PURPOSE To evaluate and compare the structural differences of the ciliary body in eyes with and without malignant glaucoma. DESIGN Cross-sectional study. PARTICIPANTS Twenty-seven consecutive patients diagnosed with malignant glaucoma in 1 eye after trabeculectomy were recruited. They were all originally diagnosed with primary angle closure (PAC) or PAC(More)
The particular microenvironment or niche plays an important role in determining the fate of stem cells and adult cells. The objective of this study was to explore the potential role of the niche of human amniotic epithelial cells in enhancing the functional properties of human corneal endothelial cells (HCECs). The HCECs were cultured in different media,(More)
The purpose of the current study was to investigate the 11 bestrophin-1 (BEST1) exons in patients with best vitelliform macular dystrophy (BVMD), and to characterize the associated clinical features. Complete ophthalmic examinations were conducted on two families, and two family members were diagnosed with BVMD. Genomic DNA was extracted from the leukocytes(More)
Locating the medial cut end of the severed canaliculus is the most difficult aspect of canalicular repair, especially in patients with more medial laceration, severe oedema, persistent errhysis and a narrow canaliculus. Irrigation is a widely used technique to identify the cut end; however, we found that air injected through the intact canaliculus with a(More)
PURPOSE To compare the repeatability and consistency of anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) in measuring iris parameters in patients with primary angle closure glaucoma. METHODS Twenty-two patients (38 eyes) with primary angle closure glaucoma, including 5 eyes with acute angle closure glaucoma, 10(More)
Canalicular laceration, especially lower canaliculus laceration, is the most common type of trauma of the lacrimal system. The primary aim of management of these cases is to restore the canalicular system both anatomically and functionally. Previously, we have successfully developed a modified soft probe to treat lacrimal passage obstruction. 2 Herein, we(More)
PURPOSE To develop a novel method to repair canalicular lacerations using silicone tubes. METHODS A total of 47 adult patients (47 eyes) with canalicular lacerations were collected from the outpatient department from November 2010 to December 2012. The age ranged from 16 to 53 years. Among the 47 eyes, 37 had lower canalicular lacerations, 6 had upper(More)