Zhiyuan Qian

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BACKGROUND We report our experience with keyhole approaches as favorable treatments for various intracranial aneurysms including multiple aneurysms and giant aneurysms. METHODS According to the different locations of 105 aneurysms harbored in 100 patients, different keyhole approaches were designed elaborately, among which a supraorbital keyhole approach(More)
Insulin-like growth factor 1 (IGF-1) is implicated in the nociceptive (pain) sensitivity of primary afferent neurons. We found that the IGF-1 receptor (IGF-1R) functionally stimulated voltage-gated T-type Ca(2+) (CaV3) channels in mouse dorsal root ganglia (DRG) neurons through a mechanism dependent on heterotrimeric G protein (heterotrimeric guanine(More)
Ca2+ plays a key role in intracellular signaling and controls various cellular processes such as proliferation, differentiation, cell growth, death, and apoptosis. Aberrant changes in intracellular Ca2+ levels can promote undesired cell proliferation and migration and are therefore associated with certain tumor types. Many research groups have suggested a(More)
The disorder to order transition and the ordered patterns near the disordered state of coil-comb copolymer A-b-(B m + 1-g-C m ) are investigated by the self-consistent field theory. The phase diagrams of coil-comb copolymer are obtained by varying the composition of the copolymer with the side chain number m = 1, 2, and 3. The disorder to order transition(More)
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