Zhixin Xu

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BACKGROUND Gantenerumab is a fully human anti-Aβ monoclonal antibody in clinical development for the treatment of Alzheimer disease (AD). OBJECTIVES To investigate whether treatment with gantenerumab leads to a measurable reduction in the level of Aβ amyloid in the brain and to elucidate the mechanism of amyloid reduction. DESIGN A multicenter,(More)
RNA-seq was used to compare the transcriptomic response of hepatopancreas in juvenile Litopenaeus vannamei fed three diets with different lipid sources, including beef tallow (BT), fish oil (FO), and an equal combination of soybean oil + BT + linseed oil (SBL) for 8 weeks at 3 practical salinity unit (psu). A total of 9622 isogenes were annotated in 316(More)
A s a typical microvascular complication and a leading cause of blindness in working-age individuals, diabetic retinopathy (DR) is a serious threat to the quality of life for millions worldwide. The prevalence of diabetic retinopathy is 22–37% in individuals with known diabetes (1,2) and 6–13% in individuals with newly diagnosed diabetes (3). However,(More)
A new ether-based electrolyte to match lithium metal electrode is prepared by introducing 1, 4-dioxane as co-solvent into lithium bis(fluorosulfonyl)imide/1,2-dimethoxyethane solution. Under the synergetic effect of solvents and salt, this simple liquid electrolyte presents stable Li cycling with dendrite-free Li deposition even at relatively high current(More)
Efficient exfoliation of well-crystallized (Y0.96Tb x Eu0.04-x )2(OH)5NO3 · nH2O (0 ≤ x ≤ 0.04) layered rare-earth hydroxide (LRH) crystals into tens of micron-sized unilamellar nanosheets has been successfully achieved by inserting water insoluble oleate anions (C17H33COO(-)) into the interlayer of the LRH via hydrothermal anion exchange at 120°C, followed(More)
Nile tilapia Oreochromis niloticus is a freshwater fish but can tolerate a wide range of salinities. The mechanism of salinity adaptation at the molecular level was studied using RNA-Seq to explore the molecular pathways in fish exposed to 0, 8, or 16 (practical salinity unit, psu). Based on the change of gene expressions, the differential genes unions from(More)
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