Zhixin Xie

Publications26
h-index16
Citations9,596
Highly Influential Citations861
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microRNA-Directed Phasing during Trans-Acting siRNA Biogenesis in Plants
Genetic and Functional Diversification of Small RNA Pathways in Plants
TLDR
It is concluded that proliferation and diversification of DCL and RDR genes during evolution of plants contributed to specialization of small RNA-directed pathways for development, chromatin structure, and defense.
Cleavage of Scarecrow-like mRNA Targets Directed by a Class of Arabidopsis miRNA
TLDR
This work shows that Arabidopsis thaliana miRNA 39 (also known as miR171), a 21-ribonucleotide species that accumulates predominantly in inflorescence tissues, is produced from an intergenic region in chromosome III and functionally interacts with mRNA targets encoding several members of the Scarecrow-like (SCL) family of putative transcription factors.
P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA unction.
DICER-LIKE 4 functions in trans-acting small interfering RNA biogenesis and vegetative phase change in Arabidopsis thaliana.
TLDR
The concept that plants have specialized and compartmentalized DCL functions for biogenesis of distinct small RNA classes for RNA interference-related processes is supported.
Negative Feedback Regulation of Dicer-Like1 in Arabidopsis by microRNA-Guided mRNA Degradation
Evolution of microRNA genes by inverted duplication of target gene sequences in Arabidopsis thaliana
TLDR
Evidence is provided that genes encoding miRNAs in plants originated by inverted duplication of target gene sequences, and a model for miRNA evolution is proposed that suggests a mechanism for de novo generation of new miRNA genes with unique target specificities.
P 1 / HC-Pro , a Viral Suppressor of RNA Silencing , Interferes with Arabidopsis Development and miRNA
TLDR
Biochemical data indicate developmental pathways that share components with that different subclasses of silencing-associated small the antiviral RNA-silencing pathway.
RNA Silencing Genes Control de Novo DNA Methylation
TLDR
Maintenance DNA methyltransferases propagate pre-existing DNA methylation in the CG sequence context by methylating hemi-methylated sites after DNA replication.
Small RNA Deep Sequencing Reveals Role for Arabidopsis thaliana RNA-Dependent RNA Polymerases in Viral siRNA Biogenesis
TLDR
An informatics analysis showed that a large set of host genes could be potentially targeted by TMV-Cg-derived siRNAs for posttranscriptional silencing, raising the interesting possibility for viral siRNA-mediated virus-host interactions that may contribute to viral pathogenicity and host specificity.
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