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The discovery of microRNAs (miRNAs) has opened a new avenue for both diagnosis and treatment of cancers. Accumulating experimental evidences indicate that miRNAs are aberrantly expressed in different tumor types and have a critical role in tumorigenesis. However, the miRNA expression profile in neuroblastoma (NB), one of the most common cancer forms in(More)
PGC-1alpha, a potent transcriptional coactivator, is the major regulator of mitochondrial biogenesis and activity in the cardiac muscle. The dysregulation of PGC-1alpha and its target genes has been reported to be associated with congenital and acquired heart diseases. By examining myocardium samples from patients with Tetralogy of Fallot, we show here that(More)
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Defining a relation between granules and computing ever-changing granules are two important issues in granular computing. In view of this, this work proposes a partial order relation and lattice computing, respectively, for dealing with the aforementioned issues. A fuzzy lattice granular computing classification algorithm, or FL-GrCCA for short, is proposed(More)
Evacuation planning is a fundamental requirement to ensure that most people can be evacuated to a safe area when a natural accident or an intentional act happens in a stadium environment. The central challenge in evacuation planning is to determine the optimum evacuation routing to safe areas. We describe the evacuation network within a stadium as a(More)
Landmarks provide the most predominant navigation cue for pedestrian navigation. Very few navigation data models in the geographical information science and transportation communities support modeling of landmarks and use of landmark-based route instructions for pedestrian navigation services. This article proposes a landmark-based pedestrian navigation(More)