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Lipid peroxidation plays an important role in cell membrane damage. We investigated the effect of lipid peroxidation on the properties of 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine (PLPC) lipid bilayers using molecular dynamics simulations. We focused on four main oxidation products of linoleic acid with either a hydroperoxide or an aldehyde(More)
The hydration free energies of amino acid side chains are an important determinant of processes that involve partitioning between different environments, including protein folding, protein complex formation, and protein-membrane interactions. Several recent papers have shown that calculated hydration free energies for polar and aromatic residues (Trp, His,(More)
Keywords: Customer integration New product development Risk evaluation Rough set theory Group AHP a b s t r a c t This study mainly focuses on the risk evaluation of customer integration in new product development. Customer integration in product innovation projects has been widely recognized a best practice to enhance innovation success rate and reduces(More)