Solid lipid nanoparticles loaded with insulin by sodium cholate-phosphatidylcholine-based mixed micelles: preparation and characterization.
Gas chromatographic-mass spectrometric analysis of d-limonene in human plasma.
Iron-Based Metal-Organic Frameworks in Drug Delivery and Biomedicine.
- Xianbin Liu, Tiantian Liang, Meiling Zhou
- Materials ScienceACS Applied Materials and Interfaces
- 19 February 2021
The present review focuses on the synthesis and surface modifications of Fe-MOFs as well as their applications in drug delivery and biomedicine.
Exosome-based biomimetic nanoparticles targeted to inflamed joints for enhanced treatment of rheumatoid arthritis
In vivo biodistribution experiment displayed FPC-Exo/Dex could preserve the bone and cartilage of CIA mice better and significantly reduce inflamed joints, and in vivo safety evaluation demonstrated this biomimetic drug delivery system had no obvious hepatotoxicity and exhibited desirable biocompatibility.
Targeted delivery of hyaluronic acid-coated solid lipid nanoparticles for rheumatoid arthritis therapy
- Meiling Zhou, Jierong Hou, Zhirong Zhong, Na Hao, Yan Lin, Chunhong Li
- Biology, MedicineDrug Delivery
- 1 January 2018
It is suggested that encapsulating glucocorticoids such as PD in HA-coated SLNs may render them safe and effective for treating inflammatory disorders.
Anionic liposomes increase the efficiency of adenovirus-mediated gene transfer to coxsackie-adenovirus receptor deficient cells.
- Zhirong Zhong, Sanjun Shi, Jianfeng Han, Zhirong Zhang, Xun Sun
- BiologyMolecular Pharmaceutics
- 1 February 2010
Anionic liposomes prepared by the calcium-induced phase change method could significantly enhance the transduction ability of Ad5 in CAR deficient cells.
Bone-targeting drug delivery system of biomineral-binding liposomes loaded with icariin enhances the treatment for osteoporosis
This drug targeting delivery system of BBL loading with icARIin showed more therapeutic advantages than the free icariin for the treatment of osteoporosis, which may be a kind of valid candidate in future osteopOrosis therapy.
Co-Delivery of Prednisolone and Curcumin in Human Serum Albumin Nanoparticles for Effective Treatment of Rheumatoid Arthritis
In AIA rats, N-PD/CU accumulated in inflamed joints through the effect of extravasation through leaky vasculature and subsequent inflammatory cell-mediated sequestration in inflammatory lesion and showed higher therapeutic efficacy than single-loaded nanoparticles, either free drug on its own, or a simple mixture of the two drugs.
Combination of adenovirus and cross-linked low molecular weight PEI improves efficiency of gene transduction
- Jianfeng Han, Dong Zhao, Zhirong Zhong, Zhirong Zhang, T. Gong, Xun Sun
- 12 March 2010
Encouraging gene transduction by Ad/PDN complexes was observed in both CAR-overexpressing cell lines and CAR-lacking cell lines, as a result of facilitating binding and cell uptake of adenoviral particles by the cationic component.
Recent Advances in Macrophage-Mediated Drug Delivery Systems
- Tiantian Liang, Rongtao Zhang, Meiling Zhou
- Biology, ChemistryInternational Journal of Nanomedicine
- 1 April 2021
This review discusses the preparation of macrophage-mediated drug delivery systems, their advantages over other delivery system, their potential applications and future lines of research.