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After a brief introduction to the basic concepts of reverse logistics, we present a two-level location problem with three types of facility to be located in a specific reverse logistics system, named a Remanufacturing Network (RMN). For this problem, we propose a 0–1 mixed integer programming model, in which we simultaneously consider “forward” and(More)
The proteomics analysis was used to search for the membrane proteins related to the type 2 diabetes in human red blood cell (RBC). To improve the solubilization and separation for membrane proteins during two-dimensional electrophoresis (2-DE), several types of chaotropes and surfactants were tested. The optimized condition was then screened. About 1000(More)
Background The single-nucleotide polymorphism (SNP) rs11191548, near the CYP17A1 gene, has been identified as being associated with hypertension and systolic blood pressure (SBP) in genome-wide association studies (GWAS) in a European population. The CYP17A1 gene encodes cytochrome P450c17alpha and plays an important role in the steroidogenic pathway, which(More)
AIM In the present study, we examined the expression and function of miR-15b in a rat model of non-alcoholic fatty liver disease (NAFLD), and we determined whether the presence of miR-15b in serum can be used as a biomarker for this disease. METHODS We measured the expression of miR-15b in both the high-fat-induced non-alcoholic fatty liver disease(More)
Variability and small lot size is a common feature for many discrete manufacturing processes designed to meet a wide array of customer needs. Because of this, job shop schedule often has to be continuously updated in reaction to changes in production plan. Generally, the aim of preventive maintenance is to ensure production effectiveness and therefore the(More)
BACKGROUND Herb-drug interactions (HDIs) resulting from concomitant use of herbal products with clinical drugs may cause adverse reactions. Organic anion transporter 1 (OAT1) and 3 (OAT3) are highly expressed in the kidney and play a key role in the renal elimination of substrate drugs. So far, little is known about the herbal extracts that could modulate(More)
Nowadays, it is an important trend in the system domain to use the software-based virtualization technology to build the execution environments (e.g., the Clouds). After introducing the virtualization layer, there exist two schedulers: One in the hypervisor and the other inside the Guest Operating System (GOS). To fully understand the virtualized system and(More)