Zhiping Mu

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BACKGROUND MicroRNAs (miRNAs), a large family of short endogenous RNAs known to post-transcriptionally repress gene expression, participate in the regulation of almost every cellular process. Changes in miRNA expression are associated with many pathologies. Ovarian folliculogenesis and testicular spermatogenesis are complex and coordinated biological(More)
The ill-conditioned inverse problem of estimating ultrasonic medium responses by deconvolution of RF signals is investigated. The primary difference between the proposed method and others is that the medium response function is assumed to be complex-valued rather than restricted to being real-valued. Derived from the complex medium model, complex Wiener(More)
Fiducial tracking is a common target tracking method widely used in image-guided procedures such as radiotherapy and radiosurgery. In this paper, we present a multifiducial identification method that incorporates context information in the process. We first convert the problem into a state sequence problem by establishing a probabilistic framework based on(More)
Coded aperture (CA) imaging originally developed in X-ray astronomy has not been widely used in nuclear medicine due to the decoding complexity of near-field CA images. In this paper, we present a near-field CA imaging technique and image reconstruction method for high sensitivity and high resolution single photon emission computerized tomography (SPECT).(More)
Digitally reconstructed radiograph (DRR) is vital to 2D/3D image registration, but computationally expensive to generate. Introduced in this paper is a novel fast DRR generation method that reuses building blocks of DRRs previously generated for known poses. The Slab algorithm is presented for illustration of the principle where projections of multiple(More)
OBJECTIVE To investigate clinical features of vertebral artery (VA) occlusion and recanalization after cervical facet dislocation. METHODS During a 2-year period from January 2014 to December 2015, 29 consecutive patients with cervical facet dislocation were treated in investigator group. VA occlusion and recanalization were identified retrospectively by(More)
In three-dimensional to two-dimensional (3D-2D) image registration, DRR (digitally reconstructed radiograph) generation is often a bottleneck in computation. In this article, a novel fast DRR generation scheme is proposed based on the recently introduced Block Projection method and Slab algorithm that reuse building blocks of DRRs previously generated for(More)
The imaging of distributed sources with near-field coded aperture (CA) remains extremely challenging and is broadly considered unsuitable for single-photon emission computerized tomography (SPECT). This study proposes a novel CA SPECT reconstruction approach and evaluates the feasibilities of imaging and reconstructing distributed hot sources and cold(More)
A multi-fiducial identification method for image guided radiotherapy and radiosurgery is presented. A modified hidden Markov model is adopted to incorporate context information. A novel algorithm, modified from the Viterbi algorithm, is introduced to identify fiducials concurrently in two orthogonal projections. This method is robust and efficient, requires(More)
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