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Direct ChIP-bisulfite sequencing reveals a role of H3K27me3 mediating aberrant hypermethylation of promoter CpG islands in cancer cells.
The model describing that aberrant CpG island (CGI) methylation leads to repression of tumour suppressor genes in cancers has been influential, but it remains unclear how such aberrancy is induced.Expand
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Improved tagmentation-based whole-genome bisulfite sequencing for input DNA from less than 100 mammalian cells.
AIM To develop a whole-genome methylation sequencing method that fulfills the needs for studies using ultra-low-input DNA. MATERIALS & METHODS The tagmentation-based whole-genome bisulfiteExpand
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Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach
BackgroundEpigenetic alterations, such as aberrant DNA methylation of promoter and enhancer regions, which lead to atypical gene expression, have been associated with carcinogenesis. InExpand
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Biocatalytic Preparation of Chiral Sulfoxides through Asymmetric Reductive Resolution by Methionine Sulfoxide Reductase A
Here we report an environmentally friendly method for the preparation of chiral sulfoxides under high substrate concentration using recombinant methionine sulfoxide reductase A from PseudomonasExpand
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Asymmetric reductive resolution of racemic sulfoxides by recombinant methionine sulfoxide reductase from a pseudomonas monteilii strain
In this study, the methionine sulfoxide reductase A from a pseudomonas monteilii strain (pmMsrA) was reported to synthesize optically active sulfoxides (R)-1a-4a, through asymmetric biocatalyticExpand
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Determinants of pro‐environmental consumption intention in rural China: The role of traditional cultures, personal attitudes and reference groups
This study aimed to identify social-psychological predictors of pro-environmental consumption intention in rural China. To this end, a proposed conceptual model was tested by analyzing the surveyExpand
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Firm response, action visibility and consumers’ legitimacy judgment
The purpose of this paper is to examine the role of action visibility in moderating the relationship between firm response and individual legitimacy judgment. Since a firm may decouple its publicExpand
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