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PURPOSE To use large-scale network (LSN) analysis to classify subjects with Alzheimer disease (AD), those with amnestic mild cognitive impairment (aMCI), and cognitively normal (CN) subjects. MATERIALS AND METHODS The study was conducted with institutional review board approval and was in compliance with HIPAA regulations. Written informed consent was(More)
We describe an audio-visual automatic continuous speech recognition system, which significantly improves speech recognition performance over a wide range of acoustic noise levels, as well as under clean audio conditions. The system utilizes facial animation parameters (FAPs) supported by the MPEG-4 standard for the visual representation of speech. We also(More)
PURPOSE To identify the neural correlates of cognitive improvement in mild Alzheimer's disease (AD) subjects following 12 weeks of donepezil treatment. MATERIALS AND METHODS Resting-state functional connectivity magnetic resonance imaging (R-fMRI) was used to measure the hippocampal functional connectivity (HFC) in 14 mild AD and 18 age-matched normal(More)
LTL cannot express the whole class of ω-regular languages and several extensions have been proposed. Among them, Quantified propositional Linear Temporal Logic (QLTL), proposed by Sistla, extends LTL by quantifications over the atomic propositions. The expressive power of LTL and its fragments have been made relatively clear by numerous researchers.(More)
Selenium (Se) is an essential trace element for humans and animals but at high concentrations, Se becomes toxic to organisms due to Se replacing sulfur in proteins. Selenium biofortification is an agricultural process that increases the accumulation of Se in crops, through plant breeding, genetic engineering, or use of Se fertilizers. Selenium(More)
Prospective studies have shown an association between depressive symptoms and cognitive impairment among older adults. However, the neural correlates of this relationship are poorly understood. Our aim was to examine whether interactive effects of memory deficits and depressive symptoms are present in the memory-associated functional networks, in(More)
Depressive symptoms often coexist with memory deficits in older adults and also are associated with incident cognitive decline in the elderly. However, little is known about the neural correlates of the association between depressive symptoms and memory deficits in nondemented elderly. Fifteen amnestic mild cognitive impairment (aMCI) and 20 cognitively(More)
The analysis of datalog programs over relational structures has been studied in depth, most notably the problem of containment. The analysis problems that have been considered were shown to be undecidable with the exception of (i) containment of arbitrary programs in nonrecursive ones, (ii) containment of monadic programs, and (iii) emptiness. In this(More)