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Recent studies about brain network have suggested that normal aging is associated with alterations in coordinated patterns of the large-scale brain functional and structural systems. However, age-related changes in functional networks constructed via positron emission tomography (PET) data are still barely understood. Here, we constructed functional brain(More)
PURPOSE Epilepsy causes a significant burden to both patients as well as society. The primary aim of this study was to calculate the factual excess costs of epilepsy in China in order to provide essential information regarding the treatment of the epilepsy for both individuals and society as a whole. METHODS This study was performed on a retrospective(More)
γ-Aminobutyric acid (GABA) is the principle inhibitory neurotransmitter in adult mammalian brain. GABA receptors B subtype (GABA(B)Rs) are abundantly expressed at presynaptic and postsynaptic neuronal structures in the rat ventrolateral periaqueductal gray (PAG), an area related to pain regulation. Activation of GABA(B)Rs by baclofen, a selective agonist,(More)
SaaS (Software as a Service) deliver software as a service over the Internet, eliminating the need to install and run the application on the customers' own computers and simplifying maintenance and support. Access control is an important information security mechanism, according to user identity and the attribution of a predefined group of users to restrict(More)
Small cell lung cancer (SCLC) is a special kind of lung cancers, lymph or blood metastasis of SCLC usually occurs in early stage. Studies in breast and colon cancer showed over expression of SATB1 could promote tumor cell growth and inhibit apoptosis. Therefore, we studied the expression of SATB1 in SCLC. The level of SATB1 was analyzed in SCLC tissues,(More)
MicroRNAs have recently emerged as key regulators of cancers, miR-329 located on 14q32.31 is one of down-regulated miRNAs in glioma, but the function and molecular mechanisms of miR-329 in determining the malignant phenotype of human glioma are elusive. This study therefore was conducted to investigate the role of miR-329 in biological behaviors of human(More)
Recently Li et al. proposed a parameter selection method for Gaussian radial basis function (GRBF) in support vector machine (SVM). In his paper cosine similarity was calculated between two vectors based on the properties of GRBF kernel function. Li's method can determine an optimal sigma in SVM and thus efficiently improve its performance, yet it is(More)
The Gaussian radial basis function (RBF) is a widely used kernel function in support vector machine (SVM). The kernel parameter σ is crucial to maintain high performance of the Gaussian SVM. Most previous studies on this topic are based on optimization search algorithms that result in large computation load. In this paper, we propose an analytical algorithm(More)
—k-nearest neighbor (k-NN) needs sufficient labeled instances for training in order to get robust performance; otherwise, performance deterioration occurs if training sets are small. In this paper, a novel algorithm, namely ordinal semi-supervised k-NN, is proposed to handle cases with a few labeled training instances. This algorithm consists of two parts:(More)