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BACKGROUND Cytochrome P450 (CYP) oxidoreductase (POR) is the electron donor for microsomal CYP enzymes. The POR Ala503Val (POR*28 C > T) polymorphism has been reported to influence CYP3A activity in vivo in a white population. The influence of this polymorphism on CYP3A activity in vivo in the Chinese population currently unknown. OBJECTIVE This study was(More)
—We present a high-performance low-power design of linear array multipliers based on a combination of the following techniques: signal flow optimization in [3:2] adder array for partial product reduction, left-to-right leapfrog (LRLF) signal flow, and splitting of the reduction array into upper/lower parts. The resulting upper/lower LRLF (ULLRLF) multiplier(More)
In this paper we present a performance-driven mapping algorithm, PLAmap, for CPLD architectures which consist of a large number of PLA-style logic cells. The primary goal of our mapping algorithm is to minimize the depth of the mapped circuit. Meanwhile, we have successfully reduced the area of the mapped circuits by applying several heuristic techniques,(More)
Flowering time, maturity, and plant morphology have considerable effects on the adaptation and grain yield of soybean (Glycine max). The identification of novel genes and an understanding of their molecular basis are critical to improve soybean productivity. In this study, we cloned a flowering time related APETALA2-like gene GmTOE4a and generated(More)
BACKGROUND Schisandra chinensis, one of the well-known traditional Chinese herbal medicines, is derived from the dry ripe fruits of Schisandra chinensis (Turcz.) Baill. according to the 9th China Pharmacopeia. Lignans are the main components isolated from extracts of S. chinensis and their content varies depending on where S. chinensis was collected. We(More)
MicroRNAs are small noncoding RNAs involved in various biological processes. We characterized the expression of miR-344-3p during mouse embryonic development. At E9.5–E10.5 and E15.5, in situ hybridization detected strong miR-344-3p signal in the central nervous system, including the cerebral cortex, hindbrain, cerebellum, thalamus, hindbrain, medulla(More)
This paper investigates the wire delay effect on the design of prefix adders when the technology moves from 250nm to 70nm. The simulation is based on parameters from NTRS'97 and uses an analytical wire delay model that considers the fanout effect and the distributive nature of wire capacitance and resistance. Simulation results show that wire delay exceeds(More)
Evidence from Los Angeles County in California, USA suggests that the relationships between wildfire burn area and fuel age, temperature, precipitation, and fuel moisture are not linear. Instead, the relationships appear to have thresholds. The data seem to support the notion that fire risk is nearly constant provided various conditions are met: that fuel(More)
BACKGROUND The aim of this study was to estimate the relationship between arterial stiffness and components of metabolic syndrome (MetS) in different age- and gender groups. METHODS A total of 12,900 Chinese adults aged 20-79 years were recruited and stratified on the basis of gender and age. All participants underwent the measurement of waist(More)