Zhihua Lu

Learn More
BACKGROUND MYST1 (also known as hMOF), a member of the MYST family of histone acetyltransferases (HATs) as an epigenetic mark of active genes, is mainly responsible for histone H4K16 acetylation in the cells. Recent studies have shown that the abnormal gene expression of hMOF is involved in certain primary cancers. Here we examined the involvement of hMOF(More)
We consider the problem of source number estimation in array processing when impulsive noise is present. To combat impulsive noise more effectively, two robust estimators with high breakdown points, i.e., the minimum covariance determinant (MCD) estimator and the MM-estimator are applied in combination with the bootstrap. The MCD estimator is applied to(More)
The problem of source enumeration in array processing is investigated. In an information theoretic criterion framework, we use in addition to the probability density function of observations, the probability density function of the sample eigenvalues obtained from the sample covariance matrix of the observations. Although the latter adds information to the(More)
This study aimed to detect protein changes that can assist to understand the underlying biology of bladder cancer. The data showed forty five proteins were found to be differentially expressed comparing tumors vs non-tumor tissues, of which EGFR and cdc2p34 were correlated with muscle invasion and histological grade. Ten proteins (ß-catenin, HSP70,(More)
BACKGROUND Radical prostatectomy (RP) carries the risk of erectile dysfunction (ED) due to cavernous nerve (CN) injury. Schwann cells are essential for the maintenance of integrity and function of peripheral nerves such as the CNs. We hypothesize that brain-derived neurotrophic factor (BDNF) activates the Janus kinase (JAK)/(signal transducer and activator(More)
BACKGROUND The effects of different modes of mechanical ventilation in the same ventilatory support level on ventilator-induced diaphragm dysfunction onset were assessed in healthy rabbits. METHODS Twenty New Zealand rabbits were randomly assigned to 4 groups (n = 5 in each group). Group 1: no mechanical ventilation; group 2: controlled mechanical(More)