Zhiguo Zheng

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—Early detection of cancer is crucial for successful treatments. High throughput and high resolution mass spectrometry are increasingly used for disease classification. In this paper a novel cancer classification method called Null space based linear discriminant analysis (NS-LDA) is proposed. NS-LDA first extracts the first order derivative information of(More)
BACKGROUND Wound healing in chronic diabetic mellitus is mainly associated with the management of angiogenesis. The angiogenic mechanism of vascular endothelial growth factor (VEGF) has been widely studied in the context of diabetic ulcers. The aim of this study was to investigate the wound-healing potential of curcumol in streptozotocin-induced diabetic(More)
Cisplatin and other platinum-based drugs have been widely used in the treatment of ovarian cancer, but most patients acquire the drug resistance that greatly compromises the efficacy of drugs. Understanding the mechanism of drug resistance is important for finding new therapeutic approaches. In the present study, we found that the expression of vimentin was(More)
Polyphyllin I (PPI) is an active component in Rhizoma Paridis, which displays extensive pharmacological antitumor activities. In a previous study, we found that polyphyllin I exhibited inhibitory effects on cell growth in the human ovarian cancer HO-8910PM cell line, as well as promoting apoptosis and the inhibition of cell migration. Furthermore, gene(More)
A micro-rotating machinery such as hard disk drive requires high efficiency and robust dynamics in high operating speed. Herringbone grooved journal bearings are widely used for this application thanks to their excellent dynamic characteristics. The clearance between sleeve and shaft is filled with fluid lubricant. However, the temperature of the fluid film(More)
In ovarian cancer treatment there is no single standard criterion adopted for chemotherapy responses assessment. CA-125 is widely used to evaluate chemotherapy responses and doctors experience still play an important role in the judgment of chemotherapy response. It is noted that there are cases whose CA125 values are in the same range but classified(More)
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