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Osteoarthritis (OA) is a degenerative joint disease that affects both cartilage and bone. A better understanding of the early molecular changes in subchondral bone may help elucidate the pathogenesis of OA. We used microarray technology to investigate the time course of molecular changes in the subchondral bone in the early stages of experimental(More)
BACKGROUND The major disadvantage of using a stem cell-based bone morphogenetic protein-4 (BMP4) gene therapy for skull defect is the overgrowth of generated bone tissue in situ. In the present study, to overcome bony overgrowth of stem cell based-gene therapy, a new strategy of two-stage bone tissue engineering by an adeno-associated virus containing BMP4(More)
Coal-fired thermal power plants, which represent the largest proportion of China's electric power system, are very sluggish in responding to power system load demands. Thus, a reasonable and feasible scheme for the medium-term optimal commitment of thermal units (MOCTU) can ensure that the generation process runs smoothly and minimizes the start-up and(More)
This paper investigates the robust monotonic convergence of discrete uncertain two-dimensional (2-D) systems described by Roesser model. The robust monotonic convergence problem of the uncertain 2-D system is firstly converted to two H<sub>&#x221E;</sub> disturbance attenuation problems of the traditional one-dimensional system. Then, the sufficient(More)
In this paper, the transportation and atomization of phosphor glue flowing in high-power LED (Light Emitting Diode) phosphor coating process were investigated via CFD (Computational Fluid Dynamics) and numerical simulations, and the 3D flow field models as well as the mathematical models of phosphor were established to describe the velocity distribution of(More)
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