Zhichao Yang

Learn More
Feistel structure is among the most popular choices for designing ciphers. Recently, 3-round/5-round integral distinguishers for Feistel structures with non-bijective/bijective round functions are presented. At EUROCRYPT 2015, Todo proposed the Division Property to effectively construct integral distinguishers for both Feistel and SPN structures. In this(More)
Enclosure partitioning approaches, such as Treemaps, have proved their effectiveness in visualizing large hierarchical structures within a compact and limited display area. Most of the Treemaps techniques do not use node-links to show the structural relations. This paper presents a new tree visualization approach known as Drawer-Tree that can be used to(More)
In the search for prodrug analogs of clopidogrel with improved metabolic characteristics and antiplatelet bioactivity, a group of clopidogrel and vicagrel analogs selectively deuterated at the benzylic methyl ester group were synthesized, characterized, and evaluated. The compounds included clopidogrel-d₃ (8), 2-oxoclopidogrel-d₃ (9), vicagrel-d₃ (10a), and(More)
O-Desmethylvenlafaxine (desvenlafaxine, ODV) is a recently approved antidepressant which in some clinical studies failed to meet a satisfactory end-point. The aim of this study was to prepare a series of phenolic esters of ODV and evaluate their potential as ODV prodrugs with improved brain uptake. Fifteen phenolic esters (compounds 1a-o) were synthesized(More)
  • 1