Zhichao Yan

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PURPOSE Since the 78 kDa glucose-regulated protein (GRP78) is a key marker of endoplasmic reticulum (ER) stress, we investigated and analyzed GRP78 expression levels in the trabecular meshwork (TM) by eyes with primary open angle glaucoma (POAG) and normal eyes to understand the role of GRP78 in human TM cells apoptosis. METHODS Trabecular meshwork cells(More)
Primary open angle glaucoma (POAG) is a neurodegenerative disease characterized by physiological intraocular hypertension that causes damage to the retinal ganglion cells (RGCs). In the past, RGC damage in POAG was suggested to have been attributed to RGC apoptosis. However, in the present study, we applied a model closer to human POAG through the use of a(More)
Parasitoid wasps are abundant and diverse hymenopteran insects that lay their eggs into the internal body (endoparasitoid) or on the external surface (ectoparasitoid) of their hosts. To make a more conducive environment for the wasps' young, both ecto- and endoparasitoids inject venoms into the host to modulate host immunity, metabolism and development.(More)
Data compression and deduplication are two common approaches to increasing storage efficiency in the cloud environment. Both users and cloud service providers have economic incentives to compress their data before storing it in the cloud. However, our analysis indicates that compressed packages of different data and differently compressed packages of the(More)
Data deduplication has become a commodity in large-scale storage systems, especially in data backup and archival systems. However, due to the removal of redundant data, data deduplication de-linearizes data placement and forces the data chunks of the same data object to be divided into multiple separate units. In our preliminary study, we found that the(More)