Zhichao Jiang

Learn More
Assessment of indirect effects is useful for epidemiologists interested in understanding the mechanisms of exposure-outcome relationships. A traditional way of estimating indirect effects is to use the "difference method," which is based on regression analysis in which one adds a possible mediator to the regression model and examines whether the coefficient(More)
This open-label, randomized phase II trial was performed to compare the efficacy and safety of nimotuzumab plus S-1 and cisplatin (NCS) versus S-1 and cisplatin (CS) alone in patients with untreated unresectable or metastatic gastric cancer in the first-line setting. Eligible participants were randomly assigned (1:1) to receive either NCS or CS. The(More)
We say that the signs of association measures among three variables {X,Y, Z} are transitive if a positive association measure between the variable X and the intermediate variable Y and further a positive association measure between Y and the endpoint variable Z imply a positive association measure between X and Z. We introduce four association measures with(More)
Manski (1997) and Manski and Pepper (2000) gave sharp bounds on causal effects under the assumptions of monotone treatment response (MTR) and monotone treatment selection (MTS). VanderWeele (2008) provided bounds for binary treatment under an assumption of monotone confounding (MC). We discuss the relation between MC and MTS and provide bounds under various(More)
Misclassification and measurement error are very common in studies of effects of exposures and are often ignored. The problem of exposure misclassification for interaction measures in the context of both multiplicative interaction (1–4) and additive interaction (5) has been discussed previously. Other investigators have discussed problems of outcome(More)
Dermatologic toxicities resulting in dose reduction or discontinuation of treatment pose challenges for targeted anticancer therapies. We conducted this randomized, double-blind, placebo-controlled trial to investigate the efficacy of topical application of Compound Danxiong Granules (CDG) for treatment of dermatologic toxicities associated with targeted(More)
  • 1