Zhibin Yuan

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Increased synthesis of endothelin-1 (ET-1) by human vascular endothelial cells (HVECs) in response to hypoxia underscores persistent vasoconstriction observed in patients with pulmonary hypertension. The molecular mechanism whereby hypoxia stimulates ET-1 gene transcription is not well understood. Here we report that megakaryocytic leukemia 1 (MKL1)(More)
Hypoxia induced pulmonary hypertension (HPH) represents a complex pathology that involves active vascular remodeling, loss of vascular tone, enhanced pulmonary inflammation, and increased deposition of extracellular matrix proteins. Megakaryocytic leukemia 1 (MKL1) is a transcriptional regulator known to influence cellular response to stress signals in the(More)
—As well-known, it is hard to detect LSB matching steganography when cover images are scans of photographs, which usually have high-frequency noise. This paper proposes a novel steganalysis method for this issue by making use of the following two facts: One is the local maxima of an image histogram decrease and the local minima increase after LSB matching(More)
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