ZhiTao Xiao

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Rheumatoid arthritis (RA) is a systemic autoimmune disease with high rates of morbidity and mortality. Previous studies proposed that the A disintegrin and metalloprotease (ADAM) family is involved in the regulation of inflammation and arthritis. Thus, the present study investigated whether ADAM10 is involved in the progression of RA. The effects of ADAM10(More)
BACKGROUND For the treatment of low back pain, the following three scenarios of posterior lumbar interbody fusion (PLIF) were usually used, i.e., PLIF procedure with autogenous iliac bone (PAIB model), PLIF with cages made of PEEK (PCP model) or titanium (Ti) (PCT model) materiel. But the benefits or adverse effects among the three surgical scenarios were(More)
Deep tissue injury (DTI) is a severe kind of pressure ulcers formed by sustained deformation of muscle tissues over bony prominences. As a major clinical issue, DTI affects people with physical disabilities, and is obviously related to the load-bearing capacity of muscle cells in various in vivo conditions. It has been hypothesized that oxidative stress,(More)
Object: To establish a non-linear finite element (FE) model for human L4–L5 lumbar segment and verify its reliability. Method: A FE model of human L4–L5 lumbar segment was established. Some empirical expressions were used to simulate the mechanical properties of vertebral body. The annulus fibrosus and nucleus were assigned hyper-elastic(More)
BACKGROUND We performed a systematic screening of colorectal cancer (CRC) tissues to investigate whether mismatch repair (MMR) status and ERCC1 protein expression could be predictive of clinical outcomes for these patients following the recommendation of The Evaluation of Genomic Applications in Practice of Prevention (EGAPP). METHODS The expression of(More)
Constructing models based on computed tomography images for finite element analysis (FEA) is challenging under pathological conditions. In the present study, an innovative method was introduced that uses Siemens syngo® 3D software for processing models and Mimics software for further modeling. Compared with the slice-by-slice traditional manual margin(More)
We observed structure and form of adult anulus fibrous of lumbar intervertebral disc at fibrous layer level. Anulus fibrosus of lumbar interverbral disc was delaminated microsurgical technique. 8 testing points were taken in each layer and the angles between their fibers going and horizontal plane were measured. We got the results: Fiber going angle at each(More)
The aim of this paper is to investigate the influence of microstructural parameters of senile vertebral cancellous bone on the apparent elastic moduli of three orthogonal directions. Thirty-six cubic regions of interest were obtained from six L4 vertebral bodies with the ages of 60–70. After scanned by a Micro-Computed Tomography (Micro-CT) system,(More)
BACKGROUND The progression of colorectal cancer (CRC) may differ depending on the location of the tumor and the age of onset of the disease. Previous studies also suggested that the molecular basis of CRC varies with tumor location, which could affect the clinical management of patients. Therefore, we performed survival analysis looking at different age(More)
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