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Upregulation of CXCR2 in tumor cells has been documented in several types of cancer. As one of its ligands, CXCL5 is associated with neutrophil infiltration and poor prognosis in hepatocellular carcinoma (HCC). However, little is known about the role of the CXCR2/CXCL5 axis in the invasion and metastasis of HCC cells. In this study, we examined CXCR2(More)
A novel easily available turn-on fluorescent chemosensor RPU based on a rhodamine-phenylurea conjugate was synthesized, which showed highly selective and sensitive recognition toward Pb(2+) in CH(3)CN and Hg(2+) in aqueous media over a wide range of tested metal ions with remarkably enhanced fluorescent intensities and also clear color changes from(More)
A novel colorimetric and fluorescent chemosensor based on a rhodamine 6G phenylurea conjugate showed highly selective and sensitive recognition toward acetate ions in H(2)O-CH(3)CN (1:1, v/v) with fluorescence intensity change and also clear color change from pink to colorless in the presence of Fe(III) ions.
Acute kidney injury (AKI) is a serious complication of sepsis, which has a high mortality rate. Growth arrest-specific protein 6 (Gas6), the protein product of the growth arrest specific gene 6, has been shown to have an anti-apoptotic effect as well as pro-survival capability. Here, we investigated the effects of Gas6 on sepsis-associated AKI in mice(More)
Expression of heterogeneous nuclear ribonucleoprotein AB (HNRNPAB) has been reported to be dysregulated in tumors, but its specific contributions to tumor formation and progression are not fully understood. Here, we demonstrate that HNRNPAB is overexpressed in highly metastatic cells and tumor tissues from patients with hepatocellular carcinoma (HCC) with(More)
CXCL5 is a member of the CXC-type chemokine family that may play a role in carcinogenesis and cancer progression. This study investigates the biological function and clinical significance of CXCL5 in intrahepatic cholangiocarcinoma (ICC). We demonstrated that CXCL5 was overexpressed in ICC cell lines and tumor samples compared with paired normal tissues.(More)
The self-alkalization of denitrifying automatic circulation (DAC) reactor resulted in a large increase of pH up to 9.20 and caused a tremendous accumulation of nitrite up to 451.1 ± 49.0 mgN L(-1) at nitrate loading rate (NLR) from 35 kgN m(-3) d(-1) to 55 kgN m(-3) d(-1). The nitrite accumulation was greatly relieved even at the same NLR once the pH was(More)
Denitratation (nitrite produced from nitrate), has the potential applications in wastewater treatment by combining with ANAMMOX process. The occurrence of denitratation has been shown to be effected qualitatively by various parameters in the environment. A more quantitative understanding can be obtained using enrichment cultures in lab-scale experiments,(More)
A coumarin-appended rhodamine derivative was prepared by reacting rhodamine hydrazide and coumarin-3-carboxylic acid, which fluorescence sensing behavior toward Zn2+ against other metal ions was investigated in CH3CN. Significantly, the rodamine-coumarin derivative exhibited highly selective and sensitive recognition toward Zn2+ with a limit of detection(More)
Recently, more and more rhodamine derivatives have been used as fluorophores to construct sensors due to their excellent spectroscopic properties. A rhodamine-based fluorescent and colorimetric Fe(3+) chemosensor 3',6'-bis(ethylamino)-2-acetoxyl-2',7'-dimethyl-spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one (RAE) was designed and synthesized. Upon the(More)