Zhi-mei Li

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Herein, a sensitive and selective sensor for biothiols based on colorimetric assay is reported. S-adenosyl-L-methionine (SAM) could induce the selective aggregation of unmodified gold nanoparticles (AuNPs) by electrostatic interaction. In the presence of biothiols, such as glutathione (GSH), homocysteine (Hcy), and cysteine (Cys), AuNPs prefer to react with(More)
OBJECTIVE To establish a model of acoustically evoked short latency negative response (ASNR) in guinea pigs, a model of profound hearing loss with normal saccular functions, and verify the correlation between ASNR and vestibular evoked myogenic potential (VEMP). METHODS Thirty-two healthy guinea pigs were employed in the experiment, which were randomly(More)
OBJECTIVE To assess and explore the quality of life and related factors among 291 outpatient adults with epilepsy. METHODS From July, 2005 to July, 2006, eligible outpatient epilepsy in a hospital was evaluated by the scale on quality of life in epilepsy-31 (Chinese version). RESULTS The total scores of quality of life was low (56.46 +/- 16.58). The(More)
BACKGROUND Recently, clinical observations reported the potential benefit of vagus nerve stimulation (VNS) for pediatric epilepsy. Transcutaneous auricular vagus nerve stimulation (ta-VNS) is a newer non-invasive VNS, making it more accessible for treating pediatric epilepsy, yet there is limited clinical evidence for its effectiveness. METHODS/DESIGN A(More)
Diabetes mellitus (DM) is a major health problem that affects patients' quality of life quality throughout the world due to its many complications. Reproductive dysfunction is one of the major secondary complications in both diabetic animals and human beings. Furthermore, DM has recently broken the age barrier and has been heavily diagnosed in children and(More)
OBJECTIVE To establish a model of ototoxicity in guinea pigs with acoustically evoked short latency negative response (ASNR) and verify the responsible organ of ASNR based on microscopic characteristics of basal membranes, saccules, utricles and ampulla canalis semicircularis of the inner ear. METHODS Total of 45 guinea pigs were employed in the(More)
OBJECTIVE To study the sub-classification of temporal lobe epilepsy (TLE) and clinical and etiological characteristics thereof. METHODS The clinical data of 190 patients with TLE, aged 1.5 approximately 67, were analyzed. The sub-classification was based on clinical manifestations and electroencephalographic recording. The etiology of TLE was mainly(More)
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