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The extended state observer first proposed by Jingqing Han in [Control and Decision , 10(1)(1995), 85-88] is the key link toward the active disturbance rejection control that is taking off as a technology after numerous successful applications in engineering. Unfortunately, there is no a rigorous proof of convergence to date. In this paper, we attempt to(More)
—In this technical note, the weak convergence of a nonlinear high-gain tracking differentiator based on finite-time stable system is presented under some easy checkable conditions. An example is constructed by using homogeneity. Numerical simulation shows that this tracking dif-ferentiator takes advantages over the existing ones. This result relaxes the(More)
BACKGROUND AND METHODS A new cyclosporin A-loaded, PEGylated chitosan-modified lipid-based nanoparticle was developed to improve upon the formulation of cyclosporin A. PEGylated chitosan, synthesized in three steps using mild reaction conditions, was used to modify the nanoparticles. Cyclosporin A-loaded, PEGylated chitosan-modified nanoparticles were(More)
The active disturbance rejection control (ADRC) was proposed by Jingqing Han in the late 1990s, which offers a new and inherently robust controller building block that requires very little information of the plant. Originally, the proposal was based largely on experiments with numerous simulations on various systems of different nature. Later, the(More)
OBJECTIVE To investigate the influnce of receptor activity modifying protein 1(RAMP-1) overexpression on enhancing effect of calcitonin gene-related peptide on MG-63 cells proliferation. METHODS Cultured MG-63 osteoblasts in exponential phase of growth were randomly divided into three groups: RAMP-1 overexpression group, empty vector control group and(More)
The extended state observer (ESO) is a key part of the active disturbance rejection control approach, a new control strategy in dealing with large uncertainty. In this paper, a nonlinear ESO is designed for a kind of lower triangular nonlinear systems with large uncertainty. The uncertainty may come from unmodeled system dynamics and external disturbance.(More)