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Using bibliometric methods, we investigate China’s international scientific collaboration from three levels of collaborating countries, institutions and individuals. We design a database in SQL Server, and make analysis of Chinese SCI papers based on the corresponding author field. We find that China’s international scientific collaboration is focused on a(More)
ABSTRACTTo solve the problem of immune incompatibility, nuclear transplantation has been envisaged as a means to produce cells or tissues for human autologous transplantation. Here we have derived embryonic stem cells by the transfer of human somatic nuclei into rabbit oocytes. The number of blastocysts that developed from the fused nuclear transfer was(More)
In our previous study (Wang et al., 2012), we analyzed scientists’ working timetable of 3 countries, using realtime downloading data of scientific literatures. In this paper, we make a through analysis about global scientists’ working habits. Top 30 countries/territories from Europe, Asia, Australia, North America, Latin America and Africa are selected as(More)
Gram-negative bacterial infection predisposes to the development of shock and acute lung injury with multiple organ dysfunction in the critically ill. Although overexpression of proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL)-1beta, IL-6, IL-8, and other mediators is causally implicated in the pathogenesis of(More)
The aim of this study was to investigate germline mutations of the APC, MUTYH and AXIN2 genes in Chinese patients with familial adenomatous polyposis (FAP), and further assess the value of bioinformatics in screening the pathogenic changes predisposing to FAP. APC genes from 11 unrelated FAP patients in Yunnan province in China were firstly examined by(More)
Val45 is a highly conserved residue and a component of the heme-pocket wall of cytochrome b(5). The crystal structures of cytochrome b(5) mutants V45E and V45Y have been determined at high resolution. Their overall structures were very similar to that of the wild-type protein. However, Val45 of the wild-type protein points towards the heme, but the large(More)
AIMS To compare the immunogenicity and anti-tumor effects of gene vaccines encoding domains 1-4 with full length of extracellular region of VEGFR2. RESULTS Both DNA vaccines decreased VEGF levels and rose specific antibodies; the lymphocyte subsets of vaccinated mice maintained high; tumor latency period and survival time of immunized mice were prolonged;(More)
A novel method is proposed to monitor and record scientists’ working timetable. We record the downloads information of scientific papers real-timely from Springer round the clock, and try to explore scientists' working habits. As our observation demonstrates, many scientists are still engaged in their research after working hours every day. Many of them(More)
In this research, we propose a method to trace scientist’s research trends realtimely. By monitoring the downloads of scientific articles in the journal of Scientometrics for 744 h, namely one month, we investigate the download statistics. Then we aggregate the keywords in these downloaded research papers, and analyze the trends of article downloading and(More)
OBJECTIVE This study aimed to evaluate the therapeutic effects of potato extract (PE) on cigarette smoke (CS)-induced chronic obstructive pulmonary disease (COPD). METHODS PE was first prepared by frozen centrifugation, and its amino acid composition was detected. Toxicity of PE was analyzed by changes in morphology, behavior, routine blood indexes, and(More)