Zhi-Juan Wu

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OBJECTIVE To study the effect of allitridum on the transient outward potassium current (Ito) of ventricular myocytes in heart failure (HF). METHODS The dual enzymatic method was used to separate single ventricular myocytes from Sprague Dawley rats. Patch-clamping was used to record Ito and analyze the effect of allitridum on the current. RESULTS The Ito(More)
OBJECTIVES To evaluate the association between a KCNQ1 mutation, R259H, and short QT syndrome (SQTS) and to explore the electrophysiological mechanisms underlying their association. METHODS We performed genetic screening of SQTS genes in 25 probands and their family members (63 patients). We used direct sequencing to screen the exons and intron-exon(More)
The varieties with erect panicles used in rice breeding have led to a significant increase in rice yield. But the molecular mechanism of erect panicle remains elusive. Oryza glumaepatula, with the erect panicle phenotype, is an excellent gene pool to improve Asian cultivated rice O. sativa. In this study, a backcross introgression line was derived with(More)
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