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Periostin was originally identified as an osteoblast-specific factor and is highly expressed in the embryonic periosteum, cardiac valves, placenta, and periodontal ligament as well as in many adult cancerous tissues. To investigate its role during development, we generated mice that lack the periostin gene and replaced the translation start site and first(More)
This paper considers the security of transmission in buffer-aided decode-and-forward cooperative wireless networks. An eavesdropper which can intercept the data transmission from both the source and relay nodes is considered to threaten the security of transmission. Finite size data buffers are assumed to be available at every relay in order to avoid having(More)
Apert syndrome is one of the most severe craniosynostosis that is mainly caused by either a Ser252Trp(S252W) or Pro253Arg(P253R) mutation in fibroblast growth factor receptor 2 (FGFR2). As an autosomal dominant disorder, Apert syndrome is mainly characterized by skull malformation resulting from premature fusion of craniofacial sutures, as well as(More)
CONTEXT Soy foods are rich in isoflavones, a major group of phytoestrogens that have been hypothesized to reduce the risk of breast cancer. However, the estrogen-like effect of isoflavones and the potential interaction between isoflavones and tamoxifen have led to concern about soy food consumption among breast cancer patients. OBJECTIVE To evaluate the(More)
Acid-sensing ion channels (ASICs) have long been considered as extracellular proton (H(+))-gated cation channels, and peripheral ASIC3 channels seem to be a natural sensor of acidic pain. Here, we report the identification of a nonproton sensor on ASIC3. We show first that 2-guanidine-4-methylquinazoline (GMQ) causes persistent ASIC3 channel activation at(More)
PURPOSE HAb18G/CD147 is a hepatocellular carcinoma (HCC)-associated antigen. We developed iodine (131I) metuximab injection (Licartin), a novel 131I-labeled HAb18G/CD147-specific monoclonal antibody Fab'2 fragment, and evaluated its safety, pharmacokinetics, and clinical efficacy on HCC in Phase I/II trials. METHODS AND MATERIALS In a Phase I trial, 28(More)
OBJECTIVES Using data from the Shanghai Breast Cancer Survival Study (SBCSS), we estimated the prevalence and perceived benefits of complementary and alternative medicine (CAM) and Chinese herbal medicine (CHM), and relevant demographic and clinical factors. DESIGN This was a cross-sectional cohort study. SUBJECTS/SETTING/LOCATION: Subjects were 5046(More)
This paper evaluates the real-time price-based demand response (DR) management for residential appliances via stochastic optimization and robust optimization approaches. The proposed real-time price-based DR management application can be imbedded into smart meters and automatically executed on-line for determining the optimal operation of residential(More)
Internet of Things (IoT) is an emerging network paradigm, which realizes the interconnections among the ubiquitous things and is the foundation of smart society. Since IoT are always related to user’s daily life or work, the privacy and security are of great importance. The pervasive, complex and heterogeneous properties of IoT make its security issues very(More)