Zhi Chai

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BACKGROUND The synthesis of bioactive nanoparticles with precise molecular level control is a major challenge in bionanotechnology. Understanding the nature of the interactions between the active components and transport biomaterials is thus essential for the rational formulation of bio-nanocarriers. The current study presents a single molecule of bovine(More)
With the trend of high-resolution imaging, computational costs of image matching have substantially increased. In order to find the compromise between accuracy and computation in real-time applications, we bring forward a fast and robust matching algorithm, named parallel and integrated matching for raw data (PIMR). This algorithm not only effectively(More)
Rho-Rho kinase (Rho-ROCK) triggers an intracellular signalling cascade that regulates cell survival, death, adhesion, migration, neurite outgrowth and retraction and influences the generation and development of several neurological disorders. Although Fasudil, a ROCK inhibitor, effectively suppressed encephalomyelitis (EAE), certain side effects may limit(More)
Parkinson’s disease (PD) is a chronic neurodegenerative disease of the central nervous system (CNS), characterized by a loss of dopaminergic neurons, which is thought to be caused by both genetic and environmental factors. Recent findings suggest that neuroinflammation may be a pathogenic factor in the onset and progression of sporadic PD. Here we explore(More)
We address the issue of deforming an image of a source object to that of a target. Previous works including barycentric coordinates and functional maps can hardly enforce shape consistency, especially for the objects with complex nested shape components. We leverage the conformal welding theory that maps 2D shapes (planar contours) to the automorphisms of(More)
In this paper, we focus on the modification of facial shapes for the purpose of efficient face beautification. The pursuit of beautiful appearance for human greatly inspires related studies. We utilize Laplacian to characterize facial geometry and adjust triangular meshes neighboring facial contour in order to beautify faces while preserving major(More)
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