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Comprehensive molecular profiling of the B7 family of immune-regulatory ligands in breast cancer.

• Zhenyu Xu, Jing Qin Shen, +12 authors Zhangang Xiao
• Oncoimmunology
• 2016

The B7 gene family has crucial roles in the regulation of adaptive cellular immunity. In cancer, deregulation of co-inhibitory B7 molecules is associated with reduced antitumor immunity and cancer… (More)

Comparison of renal interstitial fibrosis induced by different animal models of urinary tract infection

• Xiangchen Gu, Shisheng Han, Zhenyu Xu, Jie Cen, Min Chen, Yi Wang
• 2018

Long non-coding RNA PlncRNA-1 regulates cell proliferation , apoptosis , and autophagy in septic acute kidney injury by regulating BCL 2

• Dian Zheng Fu, Kai Yu Zhou, +9 authors Jinyun Dong
• 2018

This study aimed to elucidate the potential role of long non-coding RNA PlncRNA-1 in the septic acute kidney injury (AKI). The expression of PlncRNA-1 in the serum of patients with septic AKI patient… (More)

Hyperuricemia and Cardiovascular Disease.

• Shuangshuang Zhang, Yong Wang, +6 authors Dandan Zhang
• Current pharmaceutical design
• 2019

Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely… (More)

Comprehensive profiling of JMJD3 in gastric cancer and its influence on patient survival

• Zhenyu Xu, Yuan-peng Xia, +12 authors Jing Shen
• Scientific Reports
• 2018

Histone methylation is thought to control the regulation of genetic program and the dysregulation of it has been found to be closely associated with cancer. JMJD3 has been identified as an H3K27… (More)

Potentiation of the anticancer effect of doxorubicinin drug-resistant gastric cancer cells by tanshinone IIA.

• Zhenyu Xu, Haifei Chen, +11 authors Jing Shen
• Phytomedicine : international journal of…
• 2018

BACKGROUND Gastric cancer is the fifth commonest cancer and the third cause of cancer-related deaths all over the world. The effectiveness of chemotherapy is still limited by drug resistance in… (More)

Anti-tumor drug targets analysis: current insight and future prospect.

• Sheng Wang, Dexi Zhou, +4 authors Jiajie Luan
• Current drug targets
• 1969

The incidence and mortality of malignant tumors are on the rise, which has become the second leading cause of death in the world. At present, anti-tumor drugs are one of the most common methods for… (More)

Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE2 (Prostaglandin E2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury.

• Huifeng Hao, Sheng Qing Hu, +10 authors Miao Wang
• Arteriosclerosis, thrombosis, and vascular…
• 2018

OBJECTIVE Deletion of mPGES-1 (microsomal prostaglandin E synthase-1)-an anti-inflammatory target alternative to COX (cyclooxygenase)-2-attenuates injury-induced neointima formation in mice. This is… (More)

A C-type CpG ODN accelerates wound healing via regulating fibroblasts and immune response.

• Lina Li, Zhenyu Xu, Junjun Zuo, Jin Ding
• Journal of cellular biochemistry
• 2018

Abolished or delayed wound healing is a serious problem in clinical surgery, therefore, the new therapy for wound healing is needed. Synthetic oligodeoxynucleotides containing one or more CpG motifs… (More)

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