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  • Juan Ren, Yi-jin Xiao, +6 authors Yan Xu
  • Medicine, Biology
  • Cancer research
  • 2006 (First Publication: 15 March 2006)
  • Lysophosphatidic acid (LPA) is both a potential marker and a therapeutic target for ovarian cancer. It is critical to identify the sources of elevated LPA levels in ascites and blood of patients withExpand
  • Xiaoxian Zhao, Dongmei Wang, +12 authors Yan Xu
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2006 (First Publication: 29 September 2006)
  • Calcium-independent phospholipase A2 (iPLA2) plays a pivotal role in phospholipid remodeling and many other biological processes, including inflammation and cancer development. iPLA2 can be activatedExpand
  • Suthat Liangpunsakul, Yasmeen Rahmini, Ruth Alexandra Ross, Zhenwen Zhao, Yan Xu, David W Crabb
  • Medicine, Chemistry
  • American journal of physiology. Gastrointestinal…
  • 2012 (First Publication: 1 March 2012)
  • Our previous data showed the inhibitory effect of ethanol on AMP-activated protein kinase phosphorylation, which appears to be mediated, in part, through increased levels of hepatic ceramide andExpand
  • Suthat Liangpunsakul, Margaret S. Sozio, +5 authors David W Crabb
  • Medicine, Biology
  • American journal of physiology. Gastrointestinal…
  • 2010 (First Publication: 1 June 2010)
  • Ethanol treatment of cultured hepatoma cells and of mice inhibited the activity of AMP-activated protein kinase (AMPK). This study shows that the inhibitory effect of ethanol on AMPK phosphorylationExpand