Zhenrui Chen

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BACKGROUND Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema pose a challenge to conventional tractography using the standard diffusion tensor model. The aim of this study was to present a novel(More)
The aim of this study was to present a tractography algorithm using a two-tensor unscented Kalman filter (UKF) to improve the modeling of the corticospinal tract (CST) by tracking through regions of peritumoral edema and crossing fibers. Ten patients with brain tumors in the vicinity of motor cortex and evidence of significant peritumoral edema were(More)
BACKGROUND Intraoperative magnetic resonance imaging (IoMRI) was devised to overcome brain shifts during craniotomies. Yet, the acceptance of IoMRI is limited. OBJECTIVE To evaluate impact of IoMRI on intracranial glioma resection outcome including overall patient survival. METHODS A retrospective review of records was performed on a cohort of 164(More)
OBJECTIVE To construct a personalized full-length fully human antibody mammalian display library for children with systemic lupus erythematosus (SLE). METHODS The total RNA was isolated from the PBMCs of SLE children. The heavy chain variable region and kappa light chain (VH and LCκ) of the antibody genes were amplified by RT-PCR and inserted into the(More)
NI-13. RESOLVING THE CHALLENGES OF PERITUMORAL EDEMA IN TRACING ARCUATE FASCICULUS FOR SURGICAL PLANNING USING TWO-TENSOR UNSCENTED KALMAN FILTER TRACTOGRAPHY Zhenrui Chen1,4, Yanmei Tie1, Lauren O’Donnell1,2, Laura Rigolo1, Alireza Mehrtash1,2, Olutayo Olubiyi1, Isaiah Norton1, Ofer Pasternak3, Yogesh Rathi3, and Alexandra Golby1,2; Department of(More)