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Protostane Triterpenoids from the Rhizome of Alisma orientale Exhibit Inhibitory Effects on Human Carboxylesterase 2.
Twelve new and 10 known protostane triterpenoids were isolated from the rhizome of Alisma orientale. Their structures were elucidated based on physical data analyses, including UV, HRESIMS, NMR… Expand
Heliojatrones A and B, Two Jatrophane-Derived Diterpenoids with a 5/10 Fused-Ring Skeleton from Euphorbia helioscopia: Structural Elucidation and Biomimetic Conversion.
Heliojatrones A and B (1 and 2), two jatrophane-derived diterpenoids with an unprecedented trans-bicyclo[8.3.0]tridecane core, were isolated from the whole plants of Euphorbia helioscopia. Their… Expand
Biotransformation of alisol G by Penicillium janthinellum and the hCE2 inhibitory effects of its metabolites
Alisol G, also named 25-anhydroalisol A, is a major triterpene obtained from dried rhizomes of Alisma orientalis. This paper investigated the transformation of alisol G by fungi and evaluated the… Expand
Secoheliosphanes A and B and Secoheliospholane A, Three Diterpenoids with Unusual seco-Jatrophane and seco-Jatropholane Skeletons from Euphorbia helioscopia.
- Zhenpeng Mai, Gang Ni, +4 authors D. Yu
- Chemistry, Medicine
- The Journal of organic chemistry
- 5 January 2018
Secoheliosphanes A (1) and B (2) and secoheliospholane A (3), possessing an unusual 7,8-seco-jatrophane skeleton and an unprecedented 9,10-seco-7,10-epoxyjatropholane skeleton, respectively, were… Expand
Protostane alisol derivatives from the rhizome of Alisma orientale
Abstract Alisma orientalis is a well-known traditional Chinese medicine with diuretic, hypopietic, hypolipemic, and antiatherosclerotic activities. In the present study, we investigated triterpenoids… Expand
Helioscopianoids A–Q, bioactive jatrophane diterpenoid esters from Euphorbia helioscopia
The EtOH extracts of the whole plants of Euphorbia helioscopia afforded 17 new jatrophane diterpenoid esters, helioscopianoids A–Q (1—17), along with eight known compounds (18–25). Their structures… Expand
Heliosterpenoids A and B, two Novel Jatrophane-Derived Diterpenoids with a 5/6/4/6 Ring System from Euphorbia helioscopia
Heliosterpenoids A and B (1 and 2), two unprecedented jatrophane-derived diterpenoid esters with a novel 5/6/4/6-fused tetracyclic ring skeleton, were isolated from the whole plants of Euphorbia… Expand
New iridal-type triterpenoid derivatives with cytotoxic activities from Belamcanda chinensis.
Eight new iridal-type triterpenoid derivatives, including two noriridals with ether bridge (1-2); two iridals lactone (3-4), four monocyclic iridals (5-8), together with five known iridals (9-14)… Expand
Bioactive metabolites of Schisanlactone E transformed by Cunninghamella blakesleana AS 3.970.
Schisanlactone E (SE) is a major triterpene obtained from the plants of genus Kadsura. The aim of this research was to investigate the transformed metabolites of SE by fungi and evaluate the… Expand
Belamcandanes A and B, two unprecedented tricyclic-iridal triterpenoids from Belamcanda chinensis
Abstract Two unprecedented tricyclic-iridal triterpenoids, belamcandanes A–B (1–2), have been isolated from the rhizomes of Belamcanda chinensis. The structures of 1 and 2 were assigned by… Expand