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miR-7 inhibits glioblastoma growth by simultaneously interfering with the PI3K/ATK and Raf/MEK/ERK pathways.
Epidermal growth factor receptor (EGFR) signaling regulates glioblastoma cell proliferation, survival, migration and invasion and plays a key role in tumor progression. We show that microRNA-7Expand
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Recombinant Human Erythropoietin Improves the Neurofunctional Recovery of Rats Following Traumatic Brain Injury via an Increase in Circulating Endothelial Progenitor Cells
Previous studies show that circulating endothelial progenitor cells (EPCs) promote angiogenesis, which is a process associated with improved recovery in animal models of traumatic brain injury (TBI),Expand
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Poly(amido amine) is an ideal carrier of miR-7 for enhancing gene silencing effects on the EGFR pathway in U251 glioma cells.
microRNAs are regarded as promising drugs for glioma gene therapy. However, conventional administration routes, such as oral administration and intravenous infusion, presentExpand
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Survivin, a key component of the Wnt/β-catenin signaling pathway, contributes to traumatic brain injury-induced adult neurogenesis in the mouse dentate gyrus.
The enhancement of endogenous neurogenesis has been suggested in the treatment of traumatic brain injury (TBI); however, the factors that trigger the process of adult neurogenesis following TBIExpand
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Malignant behaviorial characteristics of CD133+/− glioblastoma cells from a Northern Chinese population
Following emergence of the tumor stem cell theory, the increasing number of related studies demonstrates the theory’s growing importance in cancer research and its potential for clinicalExpand
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Mesenchymal stem cells show little tropism for the resting and differentiated cancer stem cell-like glioma cells.
Intrinsic resistance of glioma cells to radiation and chemotherapy is currently hypothesized to be partially attributed to the existence of cancer stem cells. Emerging studies suggest thatExpand
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Interactions of connexin 43 and aquaporin-4 in the formation of glioma-induced brain edema.
Connexin 43 (Cx43) and aquaporin-4 (AQP4) have important roles in the formation of glioma-induced brain edema; however, the association between these two factors in the development of edema hasExpand
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Diagnosis and treatment of a dural arteriovenous fistula presenting with progressive parkinsonism and dementia: A case report and literature review
A dural arteriovenous fistula (DAVF) presenting with parkinsonism and dementia is rare; thus, is easily misdiagnosed. The present study reports the case of a 62-year-old male with mobilityExpand
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Pulmonary Function in Fur-Processing Workers: A Dose-Response Relationship
Pulmonary function tests were conducted in 212 male workers exposed to fur dust in a fur-processing factory, and in 148 unexposed male workers. The authors used the cumulative dose of dust exposureExpand
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Experimental study on fibrogenic effect of fur dust on rat lung
ObjectiveThe fibrogenicity of fur dust was studied in rat lung tissues.MethodsIntratracheal instillation of fur dust, morphologic examination of lungs and analysis of collagen content were performedExpand
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