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Chemical Constituents of the Spines of Gleditsia sinensis
The genus Gleditsia (Leguminosae) is comprised of approximately 12 specises that are widely distributed in Asia, America, and tropical Africa. Gleditsia sinensis Lam. is an endemic species in China…
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A New Lactone from the Twigs of Cinnamomum cassia
A new lactone, 5R-methyl-3-heptatriacontyl-2(5H)-furanone (1), was isolated from the twigs of Cinnamomum cassia. The structure of the new compound was established on the basis of high-resolution MS,…
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Triterpenes and lignans from the leaves of Styrax tonkinensis
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Chemical Constituents of the Rhizome of Typhonium giganteum
A new compound, gigantin (1), and seven known compounds, uridine (2), 5-(2′-methylpropyl)hydantoin (3), 5-(4′-hydroxybenzyl)hydantoin (4), 5-benzylhydantoin (5), riboflavin (6), nicotinic acid (7),…
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Total C-21 steroidal glycosides, isolated from the root tuber of Cynanchum auriculatum Royle ex Wight, attenuate hydrogen peroxide-induced oxidative injury and inflammation in L02 cells
TLDR
It is demonstrated that TCSGs can protect L02 cells against H2O2-induced oxidative toxicity and inflammatory injury by increasing the expression of Nrf2 and HO-1, mediated by the NF-κB signaling pathway.
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Antitumor evaluation and multiple analysis on different extracted fractions of the root of Cynanchum auriculatum Royle ex Wight.
TLDR
The results showed that the chloroform and ethyl acetate fractions of the root tuber suppressed tumor cell growth strongly and the C-21 steroidal glycosides based on different types of aglucones were prone in different medicinal parts of C. auriculatum.
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Chemical constituents from Mentha canadensis
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Chemical Constituents of the Aerial Parts of Lycopus lucidus var. hirtus
Chemical investigation on the aerial parts of Lycopus lucidus var. hirtus has afforded a novel abietane-type diterpenoid glycoside, lucihirtin A (1), and seven known compounds, ursolic acid…
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Bioactive Compounds from Abelmoschus manihot L. Alleviate the Progression of Multiple Myeloma in Mouse Model and Improve Bone Marrow Microenvironment
TLDR
The results of the present study indicated that the bio-active ingredients of HKC exerted protective effects on MM mouse survival through promoting osteoblastogenesis and suppressing osteoclastogenesis, thus improving the bone marrow microenvironment to inhibit MM cell proliferation.
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Flavonoids from Mentha haplocalyx
Mentha species are widely used for their flavoring and medicinal properties through out the world [1]. Mentha haplocalyx Briq., as a traditional Chinese medicine, is extensively used in the treatment…
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