Zhengliang Sun

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OBJECTIVE To investigate the relation between the expression of COX-2 protein and the effect of radiotherapy, estimate the value of COX-2 in predicting the effect of radiotherapy in patients with nasopharyngeal carcinoma,provide theoretical basement for establishing characteristic project of treatment and raising curative effect and life quantity. METHOD(More)
Epidemiological and clinico-pathological studies indicate a causal relationship between heart disease and Alzheimer's disease (AD). To learn whether heart disease causes an onset of AD, mice with myocardial infarction (MI) and congestive heart failure (HF) were used to test neuropsychiatric and cognitive behaviors as well as for measurements of AD related(More)
OBJECTIVE To investigate the effect of hyperbaric oxygen therapy to different degrees of hearing loss and different types of threshold curve in sudden deafness patients, and establish a personalized therapy, so as to promote clinical effect to sudden deafness. METHOD One hundred and twenty cases were divided into two groups respectively (each group 60(More)
OBJECTIVE To investigate the association between the shape alteration of pharyngeal ostium of eustachian tube and secretory otitis media (SOM). METHOD Two hundred and twelve pharyngeal ostiums of eustachian tube were observed by using rhinopharyngoscope and divided into two groups: the contrast's and the secretory otitis media's, and all the shape of(More)
OBJECTIVE To investigate the effects and causes of obstructive sleep apnea-hypopnea syndrome (OSAHS) on auditory pathway, the changes of auditory brainstem response (ABR) were analyzed. METHOD With the use of polysomnography,72 snorers were examined and divided into OSAHS and non- OSAHS groups. These two groups patients and a group of normal person were(More)
OBJECTIVE To investigate operative approaches and techniques of reconstruction for rhinosinusal malignant tumors involving in the anterior skull base. METHOD In a retrospective study, clinical data of 22 patients treated surgically in our department from 1988 to 2002 were analysed. Lateral rhinotomy was carried out in 8 patients and ampliative rhinotomy(More)
OBJECTIVE To develop a method for rapid screening and primary diagnosis of the nasopharyngeal carcinoma (NPC). METHOD We detected the Epstein Barr virus (EBV) DNA from nasopharynx tissue and desquamative cells in 144 suspicious NPC patients using polymerase chain reaction (PCR). The results were compared with the pathologic diagnosis. RESULT The(More)
OBJECTIVE To investigae the cause of secretory otitis media resulting from adenoids hypertrophy and the relationship between adenoids hypertrophy and secretory otitis media. METHOD According to the grades of adenoids hypertrophy, 140 children were divided into two groups: the group of middle-grade and the group of pathological hypertrophy. The effect(More)
OBJECTIVE To improve the treatment effect of atrophic rhinitis. METHOD Twenty-one cases (thirty-one sides) of atrophic rhinitis were treated by implantation of complex tissue flap to narrow the nasal cavity. RESULT Short-term effective treatment results were 100% (21/21), long-term effective treatment results were 90.5% (19/21). CONCLUSION(More)
OBJECTIVE According to the principle of Evidence-Based Medicine (EBM), to analyse the cause of SOM in patients with nasopharyngeal carcinoma (NPC) after radiotherapy and to explore the effective treatment methods of SOM in patients with NPC after radiotherapy. METHOD One hundred and six cases (112 ears) of SOM in patients with NPC after radiotherapy were(More)