Zhengchuan Hu

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In this study, the anti-proliferative effect of physcion, an anthraquinone derivative isolated and characterized from both terrestrial and marine sources, against human gastric cancer SGC-7901 cells was investigated and the underlying mechanisms were explored. Physcion reduced SGC-7901 cell viability in a dose- and time-dependent manner, as demonstrated by(More)
Prolyl hydroxylase-3 (PHD3) is an important cellular oxygen-sensor that hydroxylates substrates in an oxygen-dependent manner. PHD3 activity is required during development for the induction of apoptosis in sympathoadrenal progenitor cells. Human PHD3 localizes to the nucleus and cytoplasm, while the highly conserved rat orthologue SM20 has been reported to(More)
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