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Asperterrestide A, a cytotoxic cyclic tetrapeptide from the marine-derived fungus Aspergillus terreus SCSGAF0162.
Compound 1 contains a rare 3-OH-N-CH3-Phe residue and showed cytotoxicity against U937 and MOLT4 human carcinoma cell lines and inhibitory effects on influenza virus strains H1N1 and H3N2. Expand
Cytotoxic and antiviral nitrobenzoyl sesquiterpenoids from the marine-derived fungus Aspergillus ochraceus Jcma1F17
Both nitrobenzoyl sesquiterpenoids isolated from extracts of the culture of marine-derived fungus Aspergillus ochraceus showed significant cytotoxicities against 10 cancer cell lines, and the new one also showed antiviral activities against H3N2 and EV71. Expand
Asteltoxins with Antiviral Activities from the Marine Sponge-Derived Fungus Aspergillus sp. SCSIO XWS02F40
Two new asteltoxins named asteltoxin E (2) and F (3), and a new chromone (4), together with four known compounds were isolated from a marine sponge–derived fungus, Aspergillus sp. SCSIO XWS02F40. TheExpand
Antiviral Merosesquiterpenoids Produced by the Antarctic Fungus Aspergillus ochraceopetaliformis SCSIO 05702.
Ochraceopones A-D (1-4) are the first examples of α-pyrone merosesquiterpenoids possessing a linear tetracyclic carbon skeleton, which has not been previously described. Expand
Antituberculosis compounds from a deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01
Gliotoxin, 12,13-dihydroxy-fumitremorgin C and helvolic acid exhibited very strong anti-tuberculosis activity towards Mycobacterium tuberculosis with the prominent MIC50 values of <0.03, 2.41 and 0.894 μM, which was here reported for the first time. Expand
Cytotoxic cytochalasins from marine-derived fungus Arthrinium arundinis.
Four new cytochalasins, arthriniumnins A-D (1-4), a new natural product, ketocytochalasin (5), as well as five known cytochalasin analogues (6-10) were isolated and identified from the fungusExpand
Sydoxanthone C and acremolin B produced by deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01
A new xanthone named sydoxanthone C and a new alkaloid named acremolin B were isolated from a deep-sea-derived fungus Aspergillus sp. Expand
Arthpyrones A-C, pyridone alkaloids from a sponge-derived fungus Arthrinium arundinis ZSDS1-F3.
Three new 4-hydroxy-2-pyridone alkaloids, arthpyrones A-C (1-3), were isolated from the sponge-derived fungus Arthrinium arundinis ZSDS1-F3 and a possible biosynthetic pathway for them was proposed. Expand
Antimicrobial and antiviral sesquiterpenoids from sponge-associated fungus, Aspergillus sydowii ZSDS1-F6
This research presents a probabilistic procedure to estimate the polymethine content of the response of the H2O/O2 mixture through a number of different experimental procedures, including “situ-based,” “chemical-based” and “novel” methods. Expand
Discovery of 2-(2-aminopyrimidin-5-yl)-4-morpholino-N-(pyridin-3-yl)quinazolin-7-amines as novel PI3K/mTOR inhibitors and anticancer agents.
Results suggested that compound 17f could significantly inhibit thePI3K/Akt/mTOR pathway as a potent PI3K inhibitor and anticancer agent. Expand