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The accurate mapping of reads that span splice junctions is a critical component of all analytic techniques that work with RNA-seq data. We introduce a second generation splice detection algorithm, MapSplice, whose focus is high sensitivity and specificity in the detection of splices as well as CPU and memory efficiency. MapSplice can be applied to both(More)
We propose a class of complex population dynamic models that combines new time-varying parameters and second-order time lags for describing univariate ecological time series data. The Kalman filter and likelihood function were used to estimate parameters of all models in the class for 31 data sets, and Schwarz's information criterion (SIC) was used to(More)
Recent work has shown that recurrent neural networks have the ability to learn finite state automata from examples. In particular, networks using second-order units have been successful at this task. In studying the performance and learning behavior of such networks we have found that the second-order network model attempts to form clusters in activation(More)
—IEEE 802.11 DCF is the dominant protocol used in existing WLANs. However, the efficiency of DCF progressively degrades with the increase of contending clients in the network as well as the wireless link rate. To address this issue, in this paper, we present a distributed random media access protocol, named CHAIN, which significantly improves uplink(More)
Describes a novel neural architecture for learning deterministic context-free grammars, or equivalently, deterministic pushdown automata. The unique feature of the proposed network is that it forms stable state representations during learning-previous work has shown that conventional analog recurrent networks can be inherently unstable in that they cannot(More)
— Advances in networking, sensors, and embedded devices have made it feasible to monitor and provide medical and other assistance to people in their homes. Aging populations will benefit from reduced costs and improved healthcare through assisted living based on these technologies. However, these systems challenge current state-of-the-art techniques for(More)
—Mobile devices adopt the IEEE 802.11 PSM (Power-Saving Mode) scheme and its enhancements to reduce their energy consumption when using Wi-Fi interfaces. However , the capability of PSM to save energy is limited when the WLANs are highly congested by other Wi-Fi clients. In this paper, instead of further pursuing the trade-off between power saving and the(More)
OBJECTIVE Primary papillary serous carcinoma (PPSC) of the cervix is rarely recognized, with the aggressive and unpredictable course. Here we report a case of primary adenosquamous papillary serous carcinoma of the cervix in a woman who underwent comprehensive treatment. CASE A 53-year-old woman presented with irregular vaginal bleeding in hospital. The(More)
The fungal family Clavicipitaceae includes plant symbionts and parasites that produce several psychoactive and bioprotective alkaloids. The family includes grass symbionts in the epichloae clade (Epichloë and Neotyphodium species), which are extraordinarily diverse both in their host interactions and in their alkaloid profiles. Epichloae produce alkaloids(More)
We discuss several important issues specific to Web caching for content dynamically generated from database applications. We present the techniques employed by Oracle Web Cache to address these issues. They include: content disambiguation based on information in addition to the URL, transparent session management, partial-page caching for personalization,(More)