Learn More
MODBASE (http://salilab.org/modbase) is a relational database of annotated comparative protein structure models for all available protein sequences matched to at least one known protein structure. The models are calculated by MODPIPE, an automated modeling pipeline that relies on the MODELLER package for fold assignment, sequence-structure alignment, model(More)
We report a draft sequence for the genome of the domesticated silkworm (Bombyx mori), covering 90.9% of all known silkworm genes. Our estimated gene count is 18,510, which exceeds the 13,379 genes reported for Drosophila melanogaster. Comparative analyses to fruitfly, mosquito, spider, and butterfly reveal both similarities and differences in gene content.
Indoor localization is of great importance for a range of pervasive applications, attracting many research efforts in the past decades. Most radio-based solutions require a process of site survey, in which radio signatures of an interested area are annotated with their real recorded locations. Site survey involves intensive costs on manpower and time,(More)
Location-aware technology spawns numerous unforeseen pervasive applications in a wide range of living, production, commence, and public services. This article provides an overview of the location, localization, and localizability issues of wireless ad-hoc and sensor networks. Making data geographically meaningful, location information is essential for many(More)
The spatial features of emitted wireless signals are the basis of location distinction and determination for wireless indoor localization. Available in mainstream wireless signal measurements, the Received Signal Strength Indicator (RSSI) has been adopted in vast indoor localization systems. However, it suffers from dramatic performance degradation in(More)
Indoor localization is of great importance for a range of pervasive applications, attracting many research efforts in the past two decades. Most radio-based solutions require a process of site survey, in which radio signatures are collected and stored for further comparison and matching. Site survey involves intensive costs on manpower and time. In this(More)
BMS-754807 is a potent and reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases (Ki, <2 nmol/L). It is currently in phase I development for the treatment of a variety of human cancers. BMS-754807 effectively inhibits the growth of a broad range of human tumor types in vitro, including mesenchymal (Ewing's,(More)
In this letter, the performance of non-orthogonal multiple access (NOMA) is investigated in a cellular downlink scenario with randomly deployed users. The developed analytical results show that NOMA can achieve superior performance in terms of ergodic sum rates; however, the outage performance of NOMA depends critically on the choices of the users' targeted(More)
We compared the transcriptomes of marrow-derived mesenchymal stem cells (MSCs) with differentiated adipocytes, osteocytes, and chondrocytes derived from these MSCs. Using global gene-expression profiling arrays to detect RNA transcripts, we have identified markers that are specific for MSCs and their differentiated progeny. Further, we have also identified(More)
Structural modeling of macromolecular complexes greatly benefits from interactive visualization capabilities. Here we present the integration of several modeling tools into UCSF Chimera. These include comparative modeling by MODELLER, simultaneous fitting of multiple components into electron microscopy density maps by IMP MultiFit, computing of small-angle(More)