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Andrographolide inhibits the production of TNF-alpha and interleukin-12 in lipopolysaccharide-stimulated macrophages: role of mitogen-activated protein kinases.
TLDR
The results suggested that andrographolide inhibit LPS-induced production of TNF-alpha via suppression of the ERK1/2 signaling pathway.
Characterization of compounds in the Chinese herbal drug Mu-Dan-Pi by liquid chromatography coupled to electrospray ionization mass spectrometry.
TLDR
The large differences in chemical compounds among the three Paeonia species strongly encouraged further comparison of the bioactivities of these three species.
Inhibition of Human Cytochrome P450 Enzymes 3A4 and 2D6 by β‐Carboline Alkaloids, Harmine Derivatives
TLDR
The inhibition of the two major CYP enzymes by those β‐carboline alkaloid alkaloids suggested that changes in the pharmacokinetics of co‐administered drugs were likely to have occurred, and caution should be exercised for possible drug interactions of medicinal plants containing those β-carboline aloids and CYP substrates.
Inhibition of human liver cytochrome P450 by star fruit juice.
TLDR
Star fruit juice inhibited the seven CYP isoforms tested, with the strongest inhibitory effect against CYP2A6 and the least towards CYP3A4.
Phenolic Compounds from the Rhizomes of Dioscorea bulbifera
One new bibenzyl, 7, and one new diarylheptanone, diobulbinone A (18), together with sixteen known compounds, 1–6 and 8–17, have been isolated form the rhizomes of Dioscorea bulbifera. Their
Differentiation of Dendrobium species used as "Huangcao Shihu" by rDNA ITS sequence analysis.
TLDR
Based on the divergent ITS regions, five pairs of species-specific primers were designed and used for the rapid PCR identification of five Dendrobium species listed in the Chinese Pharmacopoeia and could be easily distinguished at the DNA level.
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