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Abscisic acid (ABA) is a vital phytohormone that regulates mainly stomatal aperture and seed development, but ABA receptors involved in these processes have yet to be determined. We previously identified from broad bean an ABA-binding protein (ABAR) potentially involved in stomatal signalling, the gene for which encodes the H subunit of Mg-chelatase (CHLH),(More)
Residents of the Tibetan Plateau show heritable adaptations to extreme altitude. We sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human genes, with an average coverage of 18x per individual. Genes showing population-specific allele frequency changes, which represent strong candidates for altitude adaptation, were(More)
To investigate possible protective effects of pyrroloquinoline quinone (PQQ) on the rat cortex with glutamate injection and to understand the mechanisms linking the in vivo neuroprotection of PQQ. Adult Sprague–Dawley rats received glutamate injection into the rat cortex. Terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling assay was(More)
With the rapid development of web video application, video similarity search has become a hot research field in content-based video retrieval. Many efforts have been carried out to improve the effectiveness and efficiency of similarity search in large database. In order to solve two challenging problems: similarity measurement and search method, a novel(More)
Variable (V) genes of immunoglobulins undergo somatic hypermutation by activation-induced deaminase (AID) to generate amino acid substitutions that encode antibodies with increased affinity for antigen. Hypermutation is restricted to germinal center B cells and cannot be recapitulated in ex vivo-activated splenic cells, even though the latter express high(More)
Radiation portal monitors are starting to be deployed at overseas ports to prevent nuclear weapons from entering the U.S. in a shipping container. Current designs have containers on trucks passing through a portal monitor at approximately 10 mph, before being routed to one of several lanes at the port's front gate for a driver identification check. For a(More)
After peripheral nerve injury, the degenerative debris and inflammatory alterations at the injury site may block the elongation of regenerating axons to reach target organs. Tissue plasminogen activator (tPA), a serine protease, has a capability of degrading matrix molecules and cell adhesions. In this study, we found that either tPA or miR-340 was(More)
This paper proposes Hi-LION, a hierarchical large-scale interconnect optical network, exploiting high-radix arrayed waveguide grating routers (AWGRs) in hierarchy to achieve very large scale and low latency interconnection of many computing nodes. By using the unique wavelength routing property of AWGRs together with electrical switching inside the(More)
By interacting with the cytoplasmic tail of a Golgi-processed form of transforming growth factor-alpha (TGFalpha), Naked2 coats TGFalpha-containing exocytic vesicles and directs them to the basolateral corner of polarized epithelial cells where the vesicles dock and fuse in a Naked2 myristoylation-dependent manner. These TGFalpha-containing(More)