Zhendong Liu

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OBJECTIVES To study the dynamics of HIV drug resistance (HIVDR) and its association with virologic and immunologic failure as well as mortality among patients on combination antiretroviral therapy (cART) in China. DESIGN We recruited 365 patients on cART in two rural Chinese counties in 2003-2004 and followed them every 6 months until May 2010. METHODS(More)
In this study, 149 F1 plants from the interspecific cross between 'Red Globe' (Vitis vinifera L.) and 'Shuangyou' (Vitis amurensis Rupr.) and the parent were used to construct a molecular genetic linkage map by using the specific length amplified fragment sequencing technique. DNA sequencing generated 41.282 Gb data consisting of 206,411,693 paired-end(More)
An F1 population was created by the cross '87-1' Â '9-22'. The female parent '87-1' was an extremely early maturing cultivar with strong flavour. The male parent was an excellent breeding line producing large berries maturing late. The mapping population included 149 randomly chosen individuals. Molecular genetic map for each parent and the consensus map(More)
Pseudoknots are a frequent RNA structure. Based on the relative stability of the stems in RNA molecules, an algorithm is presented to predict RNA pseudoknotted structure,the introduced algorithm takes O(n<sup>3</sup>) time and O(n) space and outperforms other known algorithms in predicting accuracy. This algorithm not only reduces the time complexity to(More)
Based on the relative stability of the n-stems in RNA molecules, Minimum free energy method is adopted widely to predict RNA secondary structure, a heuristic algorithm is presented to predict RNA pseudoknotted structure, the algorithm takes O(n3) time and O(n2) space. This algorithm not only reduces the time complexity to O(n3), but also widens the maximum(More)
Top-down approach has been viewed as an efficient and straightforward method to prepare nanosized zeolites. Yet, the mechanical breaking of zeolite causes amorphization, which usually requires a post-milling recrystallization to obtain fully crystalline nanoparticles. Herein we present a facile methodology to prepare zeolite nanocrystals, where milling and(More)
It is difficult to compute large RNA molecules with pseudoknots in bioinformatics, the prediction of RNA structure with pseudoknots is an NP-hard problem. According to PTAS principle and MFE models, we investigate the RNA pseudoknotted structure. We first presents an efficient algorithm for predicting RNA structure with pseudoknots. The experimental tests(More)
It is NP-hard problem of predicting RNA structure with pseudoknots. According to minimum free energy models and computational methods, we investigate the RNA pseudoknotted structure. The paper present an efficient algorithm for predicting RNA structure with pseudoknots, and the algorithm takes O (n3) time and O (n2) space. The experimental tests in Rfam10.1(More)