Author pages are created from data sourced from our academic publisher partnerships and public sources.
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma
Mitochondria are highly dynamic and undergo constant fusion and fission that are essential for maintaining physiological functions of cells. Recently, we have reported that increased mitochondrial… Expand
Angiotensin-(1-7) ameliorates myocardial remodeling and interstitial fibrosis in spontaneous hypertension: role of MMPs/TIMPs.
Angiotensin-(1-7) displays antihypertensive and antiproliferative properties although its effect on cardiac remodeling and hypertrophy in hypertension has not been fully elucidated. The present study… Expand
Long-term culture in vitro impairs the immunosuppressive activity of mesenchymal stem cells on T cells.
- Xueyi Li, Jin Ding, Z. Zheng, X. Li, Z. Wu, P. Zhu
- Medicine, Biology
- Molecular medicine reports
- 1 November 2012
Improved knowledge of the immunological properties of mesenchymal stem cells (MSCs) creates a potential cell-mediated immunotherapeutic approach for arthritic diseases. The… Expand
Chronic social stress induces cardiomyocyte contractile dysfunction and intracellular Ca2+ derangement in rats
- S. Turdi, M. Yuan, Gail M. Leedy, Z. Wu, J. Ren
- Medicine, Biology
- Physiology & Behavior
- 18 January 2012
Chronic psychosocial stress triggers cardiovascular diseases although underlying mechanisms are still elusive. This study examined the effect of social stress on cardiomyocyte contractile function… Expand
An increased major vessel uptake by 18F-FDG-PET/CT in NIH criteria inactive patients with Takayasu's arteritis.
- Q. Han, Q. Liang, Fei Kang, J. Wang, Z. Wu, P. Zhu
- Clinical and experimental rheumatology
- 7 February 2018
OBJECTIVES The commonly adopted method of defining active disease in Takayasu's arteritis (TAK) is the definition used by the US National Institutes of Health (NIH). A gold standard in imaging… Expand
Ticagrelor: Positive, negative and misunderstood properties as a new antiplatelet agent
Dual antiplatelet therapy is essential for the management of acute coronary syndrome. In particular, combination therapy using aspirin with a platelet ADP (i.e. P2Y12) receptor inhibitor, such as… Expand
Folic acid reverses nitric oxide synthase uncoupling and prevents cardiac dysfunction in insulin resistance: role of Ca2+/calmodulin-activated protein kinase II.
Nitric oxide synthase (NOS) may be uncoupled to produce superoxide rather than nitric oxide (NO) under pathological conditions such as diabetes mellitus and insulin resistance, leading to cardiac… Expand
Alterations of telomere length and mtDNA copy number are associated with overall survival in hepatocellular carcinoma patients treated with transarterial chemoembolization
PurposeIncreasing evidence suggests that alterations in mitochondrial DNA (mtDNA) copy number (mtDNAcn) and relative telomere length (RTL) may be implicated in the tumorigenesis of several… Expand
Influence of Infrasound Exposure on the Whole L-type Calcium Currents in Rat Ventricular Myocytes
This study was designed to examine the effect of infrasound exposure (5 Hz at 130 dB) on whole-cell L-type Ca2+ currents (WLCC) in rat ventricular myocytes and the underlying mechanism(s) involved.… Expand
Down-regulation of microRNA-142-3p inhibits the aggressive phenotypes of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting nuclear factor-κB signaling
- Jianhong Qiang, Tingting Lv, Zhenbiao Wu, Xichao Yang
- Biology, Medicine
- Bioscience reports
- 25 June 2019
The present study aimed to investigate the regulatory roles of miR-142-3p on the aggressive phenotypes of rheumatoid arthritis (RA) human fibroblast-like synoviocytes (RA-HFLSs), and reveal the… Expand