Novel Natural Oximes and Oxime Esters with a Vibralactone Backbone from the Basidiomycete Boreostereum vibrans
These compounds represent the first oxime esters from nature, isolated from the scale‐up fermentation broth of B. vibrans, which exhibited significant pancreatic lipase inhibitory activity and cytotoxicities against five human cancer cell lines.
Anti-Proliferative and Anti-Inflammatory Lanostane Triterpenoids from the Polish Edible Mushroom Macrolepiota procera.
12 lanostane-type triterpenoids, namely lepiotaprocerins A-L, 1-12, from the fruiting bodies of the Poland-collected edible mushroom Macrolepiota procera are isolated and distinguished by the presence of a rare "1-en-1,11-epoxy" moiety which has not been previously described in the lanostanes class.
Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens
- Zhen-Zhu Zhao, Heping Chen, Tao Feng, Zheng-Hui Li, Zejun Dong, Jikai Liu
- ChemistryNatural Products and Bioprospecting
- 10 December 2014
Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol (1), 11-hydroxyacetoxydrim-7-en-3β-ol (2), 2,6-dimethyl-7,10-epoxy-10-hydroxymethyldodeca-2,11-dien-6-ol (3), and…
Matsutakone and Matsutoic Acid, Two (Nor)steroids with Unusual Skeletons from the Edible Mushroom Tricholoma matsutake.
A novel sterol with an unprecedented polycyclic ring system, together with a new norsteroid matsutoic acid, isolated from the fruiting bodies of Tricholoma matsutake exhibited inhibitory activities against acetylcholinesterase.
(+)- and (−)-ganodilactone, a pair of meroterpenoid dimers with pancreatic lipase inhibitory activities from the macromycete Ganoderma leucocontextum
(+)- and (−)-Ganodilactone (1), a pair of novel meroterpenoid dimers possessing a unique 5′H-spiro[chroman-4,2′-furan]-2,5′-dione ring system, along with their biogeneticly-related compound,…
Cytotoxic ergosteroids from the fungus Stereum hirsutum
Lanostane Triterpenoids from Fruiting Bodies of Ganoderma leucocontextum
- Zhen-Zhu Zhao, Heping Chen, Jikai Liu
- Chemistry, MedicineNatural Products and Bioprospecting
- 12 February 2016
Six new lanostane-type triterpenoids, namely leucocontextins S–X (1–6), together with twelve known compounds, were isolated from the fruiting bodies of Ganoderma leucocontextum. Their structures were…
Terpenoids from the mushroom-associated fungus Montagnula donacina.
1,10-seco guaianolide-type sesquiterpenoids from Chrysanthemum indicum
The anti-inflammatory effects of these isolates on lipopolysaccharide (LPS)-induced nitric oxide (NO) were investigated and showed that most of the compounds displayed NO production inhibitory activities with IC50 values ranged from 3.54 to 8.17 μM.