Disruption of redox homeostasis is a prominent feature in the pathogenesis of Huntington's disease (HD). Selenium an essential element nutrient that modulates redox pathways and has been reported to provide protection against both acute neurotoxicity (e.g. methamphetamine) and chronic neurodegeneration (e.g. tauopathy) in mice. The objective of our study… (More)
BACKGROUND ARHI is a Ras-related imprinted gene that inhibits cancer cell growth and motility. ARHI is downregulated in the majority of breast cancers, and loss of its expression is associated with its progression from ductal carcinoma in situ (DCIS) to invasive disease. In ovarian cancer, re-expression of ARHI induces autophagy and leads to autophagic… (More)
Although Internet access has become more ubiquitous in recent years, most users in China still suffer from low-quality connections, especially when downloading large files. To address this issue, hundreds of millions of China's users have resorted to technologies that allow for ``<i>offline downloading</i>'', where a proxy is employed to pre-download the… (More)
Cancer antigen 125 (CA125) is a blood biomarker that is routinely used to monitor the progression of human epithelial ovarian cancer (EOC) and is encoded by MUC16, a member of the mucin gene family. The biological function of CA125/MUC16 and its potential role in EOC are poorly understood. Here we report the targeted disruption of the of the Muc16 gene in… (More)
This paper defines three types of race conditions that may occur while attempting to reserve optical circuits in GMPLS WDM networks. It then investigates the effect on network blocking by race condition type and explains how to use an already existing TLV in the IETF RSVP signaling to inform the destination node of a potential race condition occurrence. An… (More)
ErrAtum The authors have not changed the content of the original article, but would like to make the following corrections to the acknowledgments section of the published manuscript.