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Notch 3 is required for arterial identity and maturation of vascular smooth muscle cells
Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate functional arteries in mice by regulating arterial differentiation andExpand
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Sinomenine inhibits microglia activation and attenuates brain injury in intracerebral hemorrhage.
Intracerebral hemorrhage (ICH) causes morbidity and mortality and commonly follows the reperfusion after an ischemic event. Microglial activation mediated cytokine and protease secretion contributesExpand
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Cathelicidin protects against Helicobacter pylori colonization and the associated gastritis in mice
Cathelicidin, an antimicrobial peptide of the innate immune system, has been shown to modulate microbial growth, wound healing and inflammation. However, whether cathelicidin controls HelicobacterExpand
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Neuregulin attenuated cerebral ischemia–Creperfusion injury via inhibiting apoptosis and upregulating aquaporin-4
It has been demonstrated that neuregulin-1beta (NRG-1beta) plays a neuroprotective role in cerebral ischemic injury, however, its defined mechanisms and the perfect treatment window are stillExpand
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Effect of recombinant epidermal growth factor on ocular surface re-epithelization following amniotic membrane transplantation in patients with pterygium excision.
OBJECTIVE To observe the effect of recombinant human epidermal growth factor (rhEGF) on ocular surface re-epithelization and the efficacy of amniotic membrane transplantation in patients withExpand
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Experimental study on the therapeutic effects of nimustine combined with cisplatin on C6 brain glioma
Objective:To observe the synergistic effects of nimustine(ACNU) and cisplatin(CDDP) in the treatment of glioma,and investigate the theoretical basis for the combined chemotherapy in clinic.Methods:Expand
[Pathological observation of the anterior eye segment following isolation of the vessels in the rectus by microdissection].
OBJECTIVE To investigate the impact of simultaneously isolating the vessels in 4 recti of one eye by means of microdissection on the anterior segment. METHODS Among the 16 dogs, 8 received couplingExpand
Effect of bypass kinase pathways on acquired CDK4/6 inhibitor resistance.
379Background: Cyclin Dependent Kinase-4/6 (CDK4/6) kinase inhibitors have shown clinical benefit in treatment of solid tumor types, including breast cancer. However, resistance is common, and theExpand