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Ovarian cancer cells with the CD117 phenotype are highly tumorigenic and are related to chemotherapy outcome.
TLDR
This study demonstrates that human ovarian cancer cells with the CD117(+) phenotype possess the unique properties of CSCs, including self-renewal, differentiation, a high tumorigenic potential, and chemoresistance. Expand
The Mitochondrial Genome of Elodia flavipalpis Aldrich (Diptera: Tachinidae) and the Evolutionary Timescale of Tachinid Flies
TLDR
Using a Bayesian relaxed clock calibrated with fossil data, it is estimated that Tachinidae originated in the middle Eocene and maximum-likelihood and Bayesian methods supported the monophyly of both Tach inidae and superfamily Oestroidea. Expand
Antimicrobial activity-specific to Gram-negative bacteria and immune modulation-mediated NF-kappaB and Sp1 of a medaka beta-defensin.
TLDR
The obtained data suggested that the novel medaka beta-defensin should have antimicrobial activity-specific to Gram-negative bacteria, and the antibacterial immune function should be modulated by NF-kappaB and Sp1. Expand
Investigation on the rapid degradation of congo red catalyzed by activated carbon powder under microwave irradiation.
TLDR
The method using activated carbon powder as catalyst under microwave irradiation shows many advantages including high degradation ratios, short reaction time, low costs, no intermediates and no secondary pollution Therefore, it may be fit for dealing with various azo dyestuff wastewaters on a large scale. Expand
Aestuarium zhoushanense gen. nov., sp. nov., Isolated from the Tidal Flat
TLDR
On the basis of morphological, physiological, and chemotaxonomic characteristics, together with the results of phylogenetic analysis, strain G7T is described as a novel species in a new genus, for which the name Aestuarium zhoushanense gen. nov., sp. Expand
Recellularized nerve allografts with differentiated mesenchymal stem cells promote peripheral nerve regeneration
TLDR
Function and histomorphometric analysis was used to evaluate 3-month regeneration of the novel cell-supplemented tissue-engineered nerve graft used to bridge a 15-mm-long sciatic nerve gap in rats and found nerve regeneration with BMSC-SCs or ADSC- SCs was comparable to that with autografting and Schwann cells alone and better than that with acellular nerve allografts alone. Expand
Efficacy of extracorporeal shockwave therapy for knee osteoarthritis: a randomized controlled trial.
TLDR
ESWT is effective in reducing pain and improving knee function, with better results than placebo during the 12-wk treatment, however, further pilot studies are needed to determine whether ESWT should be recommended at an early or later stage of OA or combined with conventional therapies. Expand
Signature miRNAs Involved in the Innate Immunity of Invertebrates
TLDR
This study presented the first comprehensive view of the miRNAs associated with innate immunity, which would facilitate to reveal the molecular events in the regulation of innate immunity. Expand
MiR-519d represses ovarian cancer cell proliferation and enhances cisplatin-mediated cytotoxicity in vitro by targeting XIAP
TLDR
It is indicated that miR-519d suppresses cell proliferation and sensitizes ovarian cancer cells to cisplatin-induced cell death by targeting the XIAP transcript, suggesting that miD-519D plays a tumor-suppressive role in human ovarian cancer and highlighting the therapeutic potential of miR -519d in ovarian cancer treatment. Expand
Soil-borne reservoirs of antibiotic-resistant bacteria are established following therapeutic treatment of dairy calves.
TLDR
Treatment with therapeutic doses of ceftiofur or florfenicol resulted in 2-3 log more bacteria than the estimated ID50, consistent with a soil-borne reservoir emerging after antibiotic treatment that can contribute to the long-term persistence of antibiotic resistance in animal agriculture. Expand
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