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Similarity indices for high-dimensional data are very desirable for building content-based search systems for feature-rich data such as audio, images, videos, and other sensor data. Recently, locality sensitive hashing (LSH) and its variations have been proposed as indexing techniques for approximate similarity search. A significant drawback of these(More)
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Deep convolutional networks have achieved great success for visual recognition in still images. However, for action recognition in videos, the advantage over traditional methods is not so evident. This paper aims to discover the principles to design effective ConvNet archi-tectures for action recognition in videos and learn these models given limited(More)
Deep convolutional networks have achieved great success for object recognition in still images. However, for action recognition in videos, the improvement of deep convo-lutional networks is not so evident. We argue that there are two reasons that could probably explain this result. First the current network architectures (e.g. Two-stream ConvNets [12]) are(More)
The antimicrobial peptide database (APD, http://aps.unmc.edu/AP/main.php) has been updated and expanded. It now hosts 1228 entries with 65 anticancer, 76 antiviral (53 anti-HIV), 327 antifungal and 944 antibacterial peptides. The second version of our database (APD2) allows users to search peptide families (e.g. bacteriocins, cyclotides, or defensins),(More)
This system description paper introduces the OWL 2 reasoner HermiT. The reasoner is fully compliant with the OWL 2 Direct Semantics as standardised by the World Wide Web Consortium (W3C). HermiT is based on the hypertableau calculus, and it supports a wide range of standard and novel optimisations that improve the performance of reasoning on real-world(More)
Catastrophic loss of dopaminergic neurons is a hallmark of Parkinson's disease. Despite the recent identification of genes associated with familial parkinsonism, the etiology of most Parkinson's disease cases is not understood. Environmental toxins, such as the herbicide paraquat, appear to be risk factors, and it has been proposed that susceptibility is(More)
As the primary microtubule-organizing centers, centrosomes require gamma-tubulin for microtubule nucleation and organization. Located in close vicinity to centrosomes, the Golgi complex is another microtubule-organizing organelle in interphase cells. CDK5RAP2 is a gamma-tubulin complex-binding protein and functions in gamma-tubulin attachment to(More)
An antimicrobial peptide database (APD) has been established based on an extensive literature search. It contains detailed information for 525 peptides (498 antibacterial, 155 antifungal, 28 antiviral and 18 antitumor). APD provides interactive interfaces for peptide query, prediction and design. It also provides statistical data for a select group of or(More)