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Cofilin 1-Mediated Biphasic F-Actin Dynamics of Neuronal Cells Affect Herpes Simplex Virus 1 Infection and Replication
ABSTRACT Herpes simplex virus 1 (HSV-1) invades the nervous system and causes pathological changes. In this study, we defined the remodeling of F-actin and its possible mechanisms during HSV-1Expand
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miR-203 inhibits proliferation and self-renewal of leukemia stem cells by targeting survivin and Bmi-1
Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related toExpand
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Immune-enhancing activity of polysaccharides from Cyrtomium macrophyllum.
The goal of the present study was to investigate the immune-enhancing activity of polysaccharides from Cyrtomium macrophyllum (CMP). Two experiments were carried out. In immunosuppression experiment,Expand
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Immuno-enhancement effects of ethanol extract from Cyrtomium macrophyllum (Makino) Tagawa on cyclophosphamide-induced immunosuppression in BALB/c mice.
ETHNOPHARMACOLOGICAL RELEVANCE Cyrtomium macrophyllum (Makino) Tagawa has been traditionally used as a herbal medicine for the treatment of various infectious diseases such as tapeworm infestation,Expand
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  • Open Access
In vitro and in vivo anti‐inflammatory effects of theaflavin‐3,3′‐digallate on lipopolysaccharide‐induced inflammation
&NA; Inflammation is a defensive response against various harmful stimuli and stress conditions, such as tissue injury and one of the most common pathological processes occurring in human diseases.Expand
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Silencing Herpes Simplex Virus Type 1 Capsid Protein Encoding Genes by siRNA: A Promising Antiviral Therapeutic Approach
Herpes simplex virus type 1 (HSV-1), a member of the herpesviridae, causes a variety of human viral diseases globally. Although a series of antiviral drugs are available for the treatment ofExpand
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  • Open Access
Immunomodulatory effects of hydroxyethylated Hericium erinaceus polysaccharide on macrophages RAW264.7.
  • Zhe Ren, T. Qin, +5 authors Y. Huang
  • Medicine, Chemistry
  • International journal of biological…
  • 1 December 2017
Hericium erinaceus polysaccharide (HEP) has been shown to possess a variety of biological activities. In present study, HEP was successfully modified to obtain its hydroxyethylated derivative hHEP.Expand
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In vitro Anti‐Herpes Simplex Virus Activity of 1,2,4,6‐Tetra‐O‐galloyl‐β‐d‐glucose from Phyllanthus emblica L. (Euphorbiaceae)
In this study, 1,2,4,6‐tetra‐O‐galloyl‐β‐d‐glucose (1246TGG), a polyphenolic compound isolated from traditional Chinese medicine Phyllanthus emblica L. (Euphorbiaceae), was found to inhibit herpesExpand
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Selenizing Hericium erinaceus polysaccharides induces dendritic cells maturation through MAPK and NF-κB signaling pathways.
  • T. Qin, Zhe Ren, +7 authors Q. Xiao
  • Medicine, Chemistry
  • International journal of biological…
  • 1 April 2017
In this study, polysaccharides extracted from Hericium erinaceus were modified to obtain its nine selenium derivatives, sHEP1-sHEP9. Their structures were identified, yields and selenium contentsExpand
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Synthesis and in vitro anti-HSV-1 activity of a novel Hsp90 inhibitor BJ-B11.
In this study, a novel Hsp90 inhibitor BJ-B11, was synthesized and evaluated for in vitro antiviral activity against several viruses. Possible anti-HSV-1 mechanisms were also investigated. BJ-B11Expand
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